Soleno Therapeutics, Inc. (SLNO) Stock Analysis
Healthcare · Biotechnology
Sell if holding. Analyst target reached at $53.02 — A.R:R is negative (-0.9) — price has exceeded the analyst target. Reward from here is too thin for a buy — the engine flags exit. Additional concerns: Concentration risk — Product: VYKAT XR.
Soleno Therapeutics received FDA approval on March 26, 2025 for VYKAT XR (diazoxide choline extended-release), the first approved treatment for hyperphagia in Prader-Willi syndrome patients age 4+. Revenue began in Q2 2025 from VYKAT XR sales; the company had net income of... Read more
Sell if holding. Analyst target reached at $53.02 — A.R:R is negative (-0.9) — price has exceeded the analyst target. Reward from here is too thin for a buy — the engine flags exit. Additional concerns: Concentration risk — Product: VYKAT XR. Chart setup: No clear chart pattern; technical signals are mixed. Score 5.3/10, moderate confidence.
Passes 7/10 gates (positive momentum, clean insider activity, positive momentum, news events none recent, earnings proximity 55d clear, semi cycle peak clear, materials cycle peak clear). Fails on favorable risk/reward ratio. Suitability: aggressive.
Recent developments
updated 2026-06-12Recent Developments — Soleno Therapeutics, Inc.
Latest news
- NEWS SHAREHOLDER ALERT Securities Class Action Filed Against Soleno Therapeutics, Inc. (SLNO) - TMX Newsfile — TMX Newsfile negative
- NEWS Soleno Therapeutics (SLNO) Projected to Post Earnings on Wednesday - MarketBeat — MarketBeat neutral
- NEWS SLNO Q1 2026 Earnings: EPS Misses Expectations Amid Lack of Revenue - Earnings Surprise Score - thelegaladvocate.com — thelegaladvocate.com negative
- NEWS SLNO Q1 2026 Earnings: EPS Misses Expectations Amid Lack of Revenue - Revenue Beat Analysis - thelegaladvocate.com — thelegaladvocate.com negative
- NEWS Bronstein, Gewirtz & Grossman, LLC Is Investigating Soleno Therapeutics, Inc. (SLNO) And Encourages Stockholders to Conn — ACCESS Newswire negative
Generated 2026-06-15T18:11:47Z.
Upcoming dated catalysts
Thesis
Key Metrics
Quality Signals
Options Flow
Concentration Risks(10-K Item 1A)
- HIGHProductVYKAT XR10-K Item 1A: 'we have just begun to generate product revenue and are dependent upon the success of VYKAT XR'
Material Events(8-K, last 90d)
- 2026-02-26Item 5.02LOWJennifer Fulk appointed CFO effective March 2, 2026, succeeding James Mackaness who intends to retire by end of March. Fulk was previously CFO of 120Water Inc. and Talkspace, Inc. Planned succession; no disagreement cited.SEC filing →
Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.
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Rating Breakdown
2 floor-breakers·1 ceiling hit
Technicals below the gate floor. Component breakdown shows what dragged the score down.static
Priced at a premium — multiples above sector norms. Needs delivery on growth + margins to justify.static
Price Targets
Position Sizing
Risk Alerts
Earnings
Verdict History
Frequently Asked Questions
Sell if holding. Analyst target reached at $53.02 — A.R:R is negative (-0.9) — price has exceeded the analyst target. Reward from here is too thin for a buy — the engine flags exit. Additional concerns: Concentration risk — Product: VYKAT XR. Chart setup: No clear chart pattern; technical signals are mixed. Prior stop was $52.89. Score 5.3/10, moderate confidence.
Take-profit target: $60.96 (+15.0% upside). Prior stop was $52.89. Stop-loss: $52.89.
Concentration risk — Product: VYKAT XR; Analyst target reached - limited upside remaining; Expensive valuation.
Soleno Therapeutics, Inc. trades at a P/E of 27.5 (forward -23.4). TrendMatrix value score: 2.9/10. Verdict: Sell.
16 analysts cover SLNO with a consensus score of 2.7/5. Average price target: $53.
What does Soleno Therapeutics, Inc. do?Soleno Therapeutics received FDA approval on March 26, 2025 for VYKAT XR (diazoxide choline extended-release), the...
Soleno Therapeutics received FDA approval on March 26, 2025 for VYKAT XR (diazoxide choline extended-release), the first approved treatment for hyperphagia in Prader-Willi syndrome patients age 4+. Revenue began in Q2 2025 from VYKAT XR sales; the company had net income of $20.9M in 2025 but an accumulated deficit of $431.4M from prior clinical-stage losses.