BeOne Medicines combines 36% revenue growth, a Piotroski F-Score of 9/9, a wide economic moat, and a Rule of 40 score of 51 with strong analyst conviction (54% upside consensus), but the stock is in a confirmed falling knife pattern with RSI at 22, a death cross in place, and BRUKINSA product concentration risk from a single revenue driver.
Thesis pillars
- Brukinsa Concentration Growth Engine→Stable
- Wide Moat Compounder Quality→Stable
- Falling Knife Technical Setup→Stable
- +1 more pillar — see the Why tab for full reasoning
BeOne Medicines Ltd. (ONC) Stock Analysis
Recovery setup
Healthcare · Biotechnology
Hold if already holding. Not a fresh buy at $309.46, but acceptable to hold if already in. Reasons: Concentration risk — Product: BRUKINSA; Overbought (RSI 82).
BeOne Medicines discovers and commercializes oncology medicines globally, led by BRUKINSA (zanubrutinib), a BTK inhibitor approved in 77 markets, and TEVIMBRA (tislelizumab), an anti-PD-1 antibody approved in 51 markets. The company generated approximately $5.3 billion in total... Read more
Hold if already holding. Not a fresh buy at $309.46, but acceptable to hold if already in. Reasons: Concentration risk — Product: BRUKINSA; Overbought (RSI 82). Chart setup: Death cross but MACD improving, RSI 82. Maintain position. Not compelling to add more. Score 6.6/10, moderate confidence.
Passes 7/9 gates (positive momentum, clean insider activity, no SEC red flags, news boost earnings 0.70, earnings proximity 30d clear, semi cycle peak clear, materials cycle peak clear). Fails on favorable risk/reward ratio. Suitability: speculative.
Recent developments
updated 2026-07-06Recent Developments — BeOne Medicines Ltd.
Latest news
- NEWS BeOne Medicines (ONC) Receives FDA Priority Review for Tevimbra Treatment - GuruFocus — GuruFocus positive
- NEWS U.S. FDA Grants Priority Review to BeOne Medicines’ TEVIMBRA in First-Line HER2+ GEA - Business Wire — Business Wire positive
- NEWS BeOne Medicines (ONC) Reveals Promising HERIZON-GEA-01 Trial Results - GuruFocus — GuruFocus positive
- NEWS BeOne Medicines (ONC) director sells ADS to satisfy tax withholding - Stock Titan — Stock Titan negative
- NEWS BeOne Medicines (ONC) director sells 212 ADS to cover tax withholding - Stock Titan — Stock Titan negative
Generated 2026-07-06T23:11:51Z.
Upcoming dated catalysts
Thesis
Key Metrics
Quality Signals
Options Flow
Concentration Risks(10-K Item 1A)
- HIGHProductBRUKINSA10-K Item 1: 'total global revenue of approximately $5.3 billion ... BRUKINSA generated $3.9 billion in sales in 2025'
- MEDIUMGeographicChina10-K Item 1A: 'which could have a material adverse effect on our business, financial condition and results of operations in China'
Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.
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Rating Breakdown
1 floor-breaker·2 ceiling hits
Technicals below the gate floor. Component breakdown shows what dragged the score down.static
Price Targets
Position Sizing
Risk Alerts
Earnings
Verdict History
Frequently Asked Questions
Hold if already holding. Not a fresh buy at $309.46, but acceptable to hold if already in. Reasons: Concentration risk — Product: BRUKINSA; Overbought (RSI 82). Chart setup: Death cross but MACD improving, RSI 82. Maintain position. Not compelling to add more. Target $371.14 (+19.9%), stop $291.00 (−6.3%), A.R:R 1.3:1. Score 6.6/10, moderate confidence.
Take-profit target: $371.14 (+19.9% upside). Target $371.14 (+19.9%), stop $291.00 (−6.3%), A.R:R 1.3:1. Stop-loss: $291.00.
Concentration risk — Product: BRUKINSA; Overbought (RSI 82); Below 200-MA, MA slope -1.6%/30d (confirmed downtrend).
BeOne Medicines Ltd. trades at a P/E of 67.5 (forward 30.6). TrendMatrix value score: 5.4/10. Verdict: Hold.
12 analysts cover ONC with a consensus score of 4.2/5. Average price target: $412.
What does BeOne Medicines Ltd. do?BeOne Medicines discovers and commercializes oncology medicines globally, led by BRUKINSA (zanubrutinib), a BTK...
BeOne Medicines discovers and commercializes oncology medicines globally, led by BRUKINSA (zanubrutinib), a BTK inhibitor approved in 77 markets, and TEVIMBRA (tislelizumab), an anti-PD-1 antibody approved in 51 markets. The company generated approximately $5.3 billion in total revenue in 2025, with BRUKINSA contributing $3.9 billion in sales, and employs nearly 12,000 people across research, clinical, and commercial operations.