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BeOne Medicines Ltd. (ONC) Stock Analysis

HoldModerate Confidence

Healthcare · Biotechnology

BeOne Medicines AG, an oncology company, engages in discovering and developing various treatments for cancer patients in the United States, China, Europe, and internationally. The company's commercial stage products include BRUKINSA, a small molecule inhibitor of Bruton's... Read more

$286.00+23.3% upside
Score 6.0/10Target $349.39Reward/Risk 3.3:1

TrendMatrix rates BeOne Medicines Ltd. (ONC) as Hold with moderate confidence. The stock trades at $286.00 with +23.3% upside to the $349.39 price target. Overall score: 6.0/10 across 10 analysis dimensions. Reward/risk ratio: 3.3:1.

Passes 3/4 gates (favorable risk/reward ratio, clean insider activity, no SEC red flags). Fails on weak momentum. Suitability: moderate.

Val5.6Qual6.5Grw10.0Mom1.5Sent8.0Ins3.2Peer4.0Tech6.2Risk7.66.0OVERALL

Investment Thesis

+ Sector modifier (): +1.2
+ Strong earnings beat streak (3/4)
+ Strong growth profile
- Negative momentum
- Below 200-day MA

Fundamentals

P/E (TTM)111.7
P/E (Fwd)29.7
Mkt Cap$31.7B
EV/EBITDA678.6
Profit Mgn5.4%
ROE7.5%
Rev Growth32.8%
Beta0.52
DividendNone
Analysts15
Frequently Asked Questions
Is ONC stock a buy right now?

TrendMatrix rates BeOne Medicines Ltd. (ONC) as Hold with moderate confidence. Score 6.0/10.

What is the ONC stock price target?

Take-profit target: $349.39 (+23.3% upside). Reward/risk ratio: 3.3:1. Stop-loss: $263.33.

What are the risks of investing in ONC?

Negative momentum; Below 200-day MA.

Is ONC overvalued or undervalued?

BeOne Medicines Ltd. trades at a P/E of 111.7 (forward 29.7). TrendMatrix value score: 5.6/10. Verdict: Hold.

What do analysts say about ONC?

15 analysts cover ONC with a consensus score of 4.1/5. Average price target: $411.

What does BeOne Medicines Ltd. do?BeOne Medicines AG, an oncology company, engages in discovering and developing various treatments for cancer patients...

BeOne Medicines AG, an oncology company, engages in discovering and developing various treatments for cancer patients in the United States, China, Europe, and internationally. The company's commercial stage products include BRUKINSA, a small molecule inhibitor of Bruton's Tyrosine Kinase (BTK) for the treatment of various blood cancers; TEVIMBRA, an anti-PD-1 antibody immunotherapy for the treatment of various solid tumor and blood cancers; SYLVANT for the treatment of adult patients with multicentric castleman disease; BAITUOWEI for patients with BC in premenopausal and perimenopausal women, and cancer; and PARTRUVIX for the treatment of various solid tumors. Its clinical stage products comprise Sonrotoclax BGB-11417, a small molecule Bcl-2 inhibitor; BGB-16673, a BTK targeting chimeric degradation activation compound active against wild type and mutant BTK; BG-60366, an EGFR-targeted CDAC; BG-89894 (SYH2039), a MAT2A Inhibitor; BGB-58067, an MTA-Cooperative PRMT5 Inhibitor; BG-T187 and BG-C0902, an anti-EGFRxMET trispecific antibody; BGB-26808, a HPK-1 Inhibitor; BGB-C354, an anti-B7H3 ADC; Zanidatamab, a bispecific HER2-targeted antibody; BG-C137, an anti-FGFR2b ADC; BGB-53038, a Pan-KRAS Inhibitor; BGB-B2033, an anti-GPC3x4-1BB bispecific antibody; BGB-B3227, an anti-MUC1xCD16A bispecific antibody; BG-C477, an anti-CEAADC; BGB-43395, a CDK4 Inhibitor; BG-68501, a CDK2 Inhibitor; BG-C9074, an anti-B7H4 ADC; BGB-21447, a Bcl-2 Inhibitor; and BGB-45035, an IRAK4-targeted CDAC. It also has various preclinical programs. The company has agreements Amgen, BMS, Bio-Thera, EUSA Pharma, Luye Pharmaceutical, and Novartis. The company was formerly known as BeiGene, Ltd. and changed its name to BeOne Medicines AG in May 2025. BeOne Medicines AG was founded in 2010 and is based in Basel, Switzerland.

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43 NEUTRAL
<20d<50d<200dGOLDEN CROSSSupp $271.47Res $334.05

Price Targets

$263
$349
Upside+23.3%
Reward/Risk3.3:1

Position Sizing

ConvictionNONE
Suggested %0.5%
Max %1%
RegimeRISK_OFF

Risk Alerts

! MOMENTUM:1.5<5.0
RANGE BOUNDSuitability: Moderate
Risk/Reward 4.7>=2.0
Insider activity: OK
No SEC red flags
Momentum 1.5<5.0