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RAREUltragenyx Pharmaceutical Inc.Sell5.2·$25.11+3.12%
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Ultragenyx Pharmaceutical Inc. (RARE) Stock Analysis

Recovery setup

SellVALUE-TRAP 2/5Moderate Confidence

Healthcare · Biotechnology

Sell if holding. Engine safety override at $25.11: Quality below floor (2.4 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.2/10 and A.R:R 5.8:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 15%; Below-average business quality; Below long-term trend.

Ultragenyx is a late-stage biopharmaceutical company focused on rare genetic diseases, with four approved therapies (Crysvita for XLH/TIO, Mepsevii for MPS VII, Dojolvi for LC-FAOD, Evkeeza for HoFH) and multiple Phase 3 pipeline programs. Revenue comes from product sales and... Read more

$25.11+86.7% A.UpsideScore 5.2/10#79 of 157 Biotechnology
QualityF-score3 / 9FCF yield-9.14%
Stop $23.34Target $46.85(analyst − 10%)A.R:R 5.8:1
Analyst target$52.05+107.3%19 analysts
$46.85our TP
$25.11price
$52.05mean
$96

Sell if holding. Engine safety override at $25.11: Quality below floor (2.4 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.2/10 and A.R:R 5.8:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 15%; Below-average business quality; Below long-term trend. Chart setup: Death cross but MACD improving, RSI 60. Score 5.2/10, moderate confidence.

Passes 8/9 gates (positive momentum, favorable risk/reward ratio, clean insider activity, no SEC red flags, news events none recent, earnings proximity 50d clear, semi cycle peak clear, materials cycle peak clear). Suitability: aggressive.

news + 30-day 8-K events · 5-min refresh

Recent developments

updated 2026-06-15

Recent Developments — Ultragenyx Pharmaceutical Inc.

Generated 2026-06-15T18:11:47Z.

TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Tue, Aug 4, 202650d to earnings· next earnings call

Thesis

Rewards
No bull case signals
Risks
Quality below floor (2.4 < 4.0)
Value-trap signals (2/5): Revenue declining (-11.6% YoY), Margin compression (op margin 1.5%)

Key Metrics

P/E (TTM)
P/E (Fwd)25.2
Mkt Cap$2.4B
EV/EBITDA-6.4
Profit Mgn-90.9%
ROE
Rev Growth-2.2%
Beta0.38
DividendNone
Rating analysts25

Quality Signals

Piotroski F3/9

Options Flow

P/C0.46bullish
IV74%elevated
Max Pain$15-40.3% vs spot

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.

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Methodology · Editorial policy & full disclaimer

Rating Breakdown

3 floor-breakers

Technicals below the gate floor. Component breakdown shows what dragged the score down.static

Bollinger
0.0
Support Resistance
0.4
52w Position
1.8
Gap
5.0

Unprofitable operations — net margin -90.9%. Quality floor flags this regardless of sector context.static

Roa
0.0
Net Margin
0.0
Fcf Quality
0.0
Piotroski F
3.3
Moat
3.8
Current Ratio
7.1
Cash-burning: FCF -33% of revenueNo competitive moatWeak Piotroski F-Score: 3/9Quality concerns

No near-term catalyst priced in. Thesis progression will come from fundamentals grinding, not event reaction.static

Earnings History
0.0
Surprise Avg
0.0
Erm
5.0
Earnings Timing
5.0
Earnings concerns: 1B/3M
GatesDeath cross (50MA < 200MA)Momentum 6.1>=5.5A.R:R 5.8 ≥ 1.5Insider activity: OKNo SEC red flagsNEWS EVENTS NONE RECENTEARNINGS PROXIMITY 50d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARRecoverySuitability: Aggressive
RSI
60 · Neutral
20D MA 50D MA 200D MADEATH CROSSSupport $21.33Resistance $25.25

Price Targets

$23
$47
A.Upside+86.6%
A.R:R5.8:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Quality below floor (2.4 < 4.0)
! Value-trap signals (2/5): Revenue declining (-11.6% YoY), Margin compression (op margin 1.5%)

Earnings

B
M
M
M
1/4 beats
Next Earnings2026-08-04 (50d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is RARE stock a buy right now?

Sell if holding. Engine safety override at $25.11: Quality below floor (2.4 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.2/10 and A.R:R 5.8:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 15%; Below-average business quality; Below long-term trend. Chart setup: Death cross but MACD improving, RSI 60. Prior stop was $23.34. Score 5.2/10, moderate confidence.

What is the RARE stock price target?

Take-profit target: $46.85 (+86.7% upside). Prior stop was $23.34. Stop-loss: $23.34.

What are the risks of investing in RARE?

Quality below floor (2.4 < 4.0); Value-trap signals (2/5): Revenue declining (-11.6% YoY), Margin compression (op margin 1.5%).

Is RARE overvalued or undervalued?

Ultragenyx Pharmaceutical Inc. trades at a P/E of N/A (forward 25.2). TrendMatrix value score: 8.0/10. Verdict: Sell.

What do analysts say about RARE?

25 analysts cover RARE with a consensus score of 4.2/5. Average price target: $52.

What does Ultragenyx Pharmaceutical Inc. do?Ultragenyx is a late-stage biopharmaceutical company focused on rare genetic diseases, with four approved therapies...

Ultragenyx is a late-stage biopharmaceutical company focused on rare genetic diseases, with four approved therapies (Crysvita for XLH/TIO, Mepsevii for MPS VII, Dojolvi for LC-FAOD, Evkeeza for HoFH) and multiple Phase 3 pipeline programs. Revenue comes from product sales and collaboration payments from Kyowa Kirin (KKC) and Gilead; as of December 31, 2025, available cash was $737M. The company is implementing a 10% workforce reduction (~130 employees) and ~$50M in restructuring charges in H1 2026 following UX143 Phase 3 failures.

Related stocks: INCY (Incyte Corporation) · AUPH (Aurinia Pharmaceuticals Inc) · HALO (Halozyme Therapeutics, Inc.) · AAPG (Ascentage Pharma Group Internat) · INVA (Innoviva, Inc.)
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