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KNSAKiniksa Pharmaceuticals InternaSell6.4·$52.78+2.33%
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Kiniksa Pharmaceuticals Interna (KNSA) Stock Analysis

Breakout setup

SellModerate Confidence

Healthcare · Drug Manufacturers - Specialty & Generic

Sell if holding. At $52.78, A.R:R 0.6:1 is below the 1.5:1 minimum. Reward from here is too thin for a buy — the engine flags exit. Additional concerns: Thin upside margin: 6.5%; Leverage penalty (D/E 1.5): -0.5.

Kiniksa Pharmaceuticals is a commercial-stage biopharmaceutical company with ARCALYST (rilonacept) approved in the US, EU, and Japan for dystrophic epidermolysis bullosa and other IL-1-mediated conditions. Revenue comes almost entirely from ARCALYST US sales ($730.3M cumulative... Read more

QualityF-score8 / 9FCF yield2.94%
Stop $48.26Target $55.24(analyst − 13%)A.R:R 0.6:1
Analyst target$63.50+20.3%8 analysts
$55.24our TP
$52.78price
$63.50mean
$72

Sell if holding. At $52.78, A.R:R 0.6:1 is below the 1.5:1 minimum. Reward from here is too thin for a buy — the engine flags exit. Additional concerns: Thin upside margin: 6.5%; Leverage penalty (D/E 1.5): -0.5. Chart setup: Golden cross, above all MAs, RSI 45, MACD bullish. Score 6.4/10, moderate confidence.

Passes 7/8 gates (positive momentum, clean insider activity, no SEC red flags, news events none recent, earnings proximity 43d clear, semi cycle peak clear, materials cycle peak clear). Fails on favorable risk/reward ratio. Suitability: aggressive.

news + 30-day 8-K events · 5-min refresh

Recent developments

updated 2026-06-15
TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Tue, Jul 28, 202643d to earnings· next earnings call

Thesis

Rewards
Strong growth profile
Risks
Thin upside margin: 6.5%
Leverage penalty (D/E 1.5): -0.5
Consecutive earnings misses (3)

Key Metrics

P/E (TTM)57.0
P/E (Fwd)29.5
Mkt Cap$4.0B
EV/EBITDA37.2
Profit Mgn9.7%
ROE13.7%
Rev Growth55.5%
Beta0.12
DividendNone
Rating analysts14

Quality Signals

Piotroski F8/9MoatNarrow

Options Flow

P/C0.32bullish
IV108%elevated
Max Pain$25-52.6% vs spot

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.

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Methodology · Editorial policy & full disclaimer

Rating Breakdown

1 floor-breaker·1 ceiling hit

No near-term catalyst priced in. Thesis progression will come from fundamentals grinding, not event reaction.static

Earnings History
0.0
Surprise Avg
0.0
Erm
5.0
Earnings Timing
5.0
Earnings concerns: 1B/3M
GatesA.R:R 0.6 < 1.5@spotMomentum 6.4>=5.5Insider activity: OKNo SEC red flagsNEWS EVENTS NONE RECENTEARNINGS PROXIMITY 43d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARBreakoutSuitability: Aggressive
RSI
45 · Neutral
20D MA 50D MA 200D MAGOLDEN CROSSSupport $46.10Resistance $58.56

Price Targets

$48
$55
A.Upside+4.7%
A.R:R0.6:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! NEWS_MOD=-1: HOLD_IF_HOLDING → SELL_IF_HOLDING
! asymmetry at 0.6 (below the engine's 1.5 threshold)@spot

Earnings

B
M
M
M
1/4 beats
Next Earnings2026-07-28 (43d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is KNSA stock a buy right now?

Sell if holding. At $52.78, A.R:R 0.6:1 is below the 1.5:1 minimum. Reward from here is too thin for a buy — the engine flags exit. Additional concerns: Thin upside margin: 6.5%; Leverage penalty (D/E 1.5): -0.5. Chart setup: Golden cross, above all MAs, RSI 45, MACD bullish. Prior stop was $48.26. Score 6.4/10, moderate confidence.

What is the KNSA stock price target?

Take-profit target: $55.24 (+6.5% upside). Prior stop was $48.26. Stop-loss: $48.26.

What are the risks of investing in KNSA?

Thin upside margin: 6.5%; Leverage penalty (D/E 1.5): -0.5; Consecutive earnings misses (3).

Is KNSA overvalued or undervalued?

Kiniksa Pharmaceuticals Interna trades at a P/E of 57.0 (forward 29.5). TrendMatrix value score: 5.2/10. Verdict: Sell.

What do analysts say about KNSA?

14 analysts cover KNSA with a consensus score of 4.3/5. Average price target: $64.

What does Kiniksa Pharmaceuticals Interna do?Kiniksa Pharmaceuticals is a commercial-stage biopharmaceutical company with ARCALYST (rilonacept) approved in the US,...

Kiniksa Pharmaceuticals is a commercial-stage biopharmaceutical company with ARCALYST (rilonacept) approved in the US, EU, and Japan for dystrophic epidermolysis bullosa and other IL-1-mediated conditions. Revenue comes almost entirely from ARCALYST US sales ($730.3M cumulative since launch); the pipeline includes KPL-387 (Phase 2/3 for recurrent pericarditis) and KPL-1161 (preclinical).

Related stocks: NBIX (Neurocrine Biosciences, Inc.) · ANIP (ANI Pharmaceuticals, Inc.) · INDV (Indivior Pharmaceuticals, Inc.) · COLL (Collegium Pharmaceutical, Inc.) · BHC (Bausch Health Companies Inc.)
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