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BBIOBridgeBio Pharma, Inc.Sell5.8·$70.82
SellModerate Confidence
Investment thesis

BridgeBio is growing revenue 120% YoY with 41.5% upside to the analyst target, but it burns cash at -45% of revenue, has missed earnings in 3 of 4 quarters, depends on two products and faces insider selling.

Thesis pillars

  • Hypergrowth Launch→Stable
  • Cash Burn Despite Growth→Stable
  • Two Product Concentration↓Deteriorating
  • +2 more pillars — see the Why tab for full reasoning

Pillars as of Oct 24, 2026, based on the 10-K filed Feb 24, 2026

Full reasoning →

Open full analysis

BridgeBio Pharma, Inc. (BBIO) Stock Analysis

Recovery setup

SellGrowthModerate Confidence

Healthcare · Biotechnology

Earnings today — results expected after close (2026-10-29). Expect elevated volatility around the report — consider waiting for post-earnings price action before new entries.

Sell if holding. Engine safety override at $70.82: Quality below floor (4.0 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.8/10 and A.R:R 3.3:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 11%; Elevated put/call ratio: 6.33; Below-average business quality.

BridgeBio Pharma commercializes Attruby (acoramidis) for ATTR-CM in the U.S. and develops therapies for genetic diseases. Attruby generated $362.4 million in U.S. net product revenues in 2025; Beyonttra contributed $105.0 million in license revenue via Bayer (Europe) and Alexion... Read more

$70.82+37.0% A.UpsideScore 5.8/10#62 of 241 Biotechnology
QualityF-score4 / 9FCF yield-2.31%
Stop $66.90Analyst target $97.03(−10% haircut)A.R:R 3.3:1
Analyst consensus$107.81+52.2%21 analysts
$97.03Analyst target
$70.82price
$107.81mean
$156

Sell if holding. Engine safety override at $70.82: Quality below floor (4.0 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.8/10 and A.R:R 3.3:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 11%; Elevated put/call ratio: 6.33; Below-average business quality. Chart setup: Death cross but MACD improving, RSI 71. Score 5.8/10, moderate confidence.

Passes 7/9 gates (positive momentum, favorable risk/reward ratio, clean insider activity, no SEC red flags, news events none recent, semi cycle peak clear, materials cycle peak clear). Fails on earnings proximity 0d<=7d. Suitability: speculative.

news + 30-day 8-K events · 5-min refresh

Recent developments

updated 2026-10-29
TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Thu, Oct 29, 2026Earnings today — results expected after close· next earnings call

Thesis

Rewards
No bull case signals
Risks
Concentration risk — Product: Attruby and Beyonttra
Quality below floor (4.0 < 4.0)

Key Metrics

P/E (TTM)—
P/E (Fwd)-315.3
Mkt Cap$13.8B
EV/EBITDA-34.9
Profit Mgn-97.0%
ROE—
Rev Growth120.4%
Beta0.97
DividendNone
Rating analysts29

Quality Signals

Piotroski F4/9MoatNarrow

Options Flow

P/C6.33bearish
IV57%elevated
Max Pain$88+23.6% vs spot

Concentration Risks(10-K Item 1A)

  • HIGHProductAttruby and Beyonttra
    10-K Item 1A: 'Our business is substantially dependent on the commercial success of Attruby and Beyonttra'

Material Events(8-K, last 90d)

  • 2026-05-08Item 1.01LOW
    BridgeBio entered an Equity Distribution Agreement with Goldman Sachs and Leerink Partners on May 7, 2026 for an at-the-market offering of up to $500 million in common stock, filed alongside a Form S-3ASR registration statement.
    SEC filing →

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results. How we score · Editorial policy

Show full disclosure ▾

About TrendMatrix. TrendMatrix is a publisher of general securities research and market commentary. We publish on a regular schedule. All content is the same for every subscriber in a tier — we do not provide personalized investment advice and we do not take into account any individual subscriber's financial situation, investment objectives, risk tolerance, tax situation, or holdings.

Not investment advice. TrendMatrix is not a registered investment adviser. Our content is for informational and educational purposes only. Consult your own licensed investment adviser, broker, or tax professional before making any investment decision.

Conflicts and positions. People who build TrendMatrix, or entities they control, may hold positions, long or short, in securities it covers, and may trade them at any time. Positions are not disclosed individually. Verdicts are generated by an automated model applied by the same rules to every covered stock, and are not adjusted for any position held by the people who build TrendMatrix. We do not accept payment from issuers for coverage.

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Performance. Past performance is not indicative of future results. Performance figures reflect the published model only and do not reflect any individual subscriber's actual results.

Methodology · Editorial policy & full disclaimer

Rating Breakdown

2 floor-breakers·1 ceiling hit

Technicals below the gate floor. Component breakdown shows what dragged the score down.static

Bollinger
0.0
Support Resistance
0.4
52w Position
5.2

No near-term catalyst priced in. Thesis progression will come from fundamentals grinding, not event reaction.static

Earnings History
0.0
Surprise Avg
0.0
Erm
5.0
Earnings Timing
5.0
Earnings concerns: 1B/3MEarnings today
GatesEARNINGS PROXIMITY 0d<=7dDeath cross (50MA < 200MA)Momentum 6.7>=5.5A.R:R 3.3 ≥ 1.5Insider activity: OKNo SEC red flagsNEWS EVENTS NONE RECENTSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARRecoverySuitability: Speculative
RSI
71 · Overbought
↑ 20D MA↑ 50D MA↓ 200D MADEATH CROSSSupport $62.86Resistance $71.18

Price Targets

$67
$97
A.Upside+37.0%
A.R:R3.3:1

Position Sizing

ConvictionNone
Suggested %0%
Max %0%
RegimeSteady

Risk Alerts

! Quality below floor (4.0 < 4.0)
! EARNINGS_PROXIMITY:0d<=7d

Earnings

B
M
M
M
1/4 beats
Next Earnings2026-10-29 (Earnings today — results expected after close)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is BBIO stock a buy right now?

Sell if holding. Engine safety override at $70.82: Quality below floor (4.0 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.8/10 and A.R:R 3.3:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 11%; Elevated put/call ratio: 6.33; Below-average business quality. Chart setup: Death cross but MACD improving, RSI 71. Prior stop was $66.90. Score 5.8/10, moderate confidence.

What is the BBIO stock price target?

Analyst target: $97.03 (+37.0% upside). Prior stop was $66.90. Stop-loss: $66.90.

What are the risks of investing in BBIO?

Concentration risk — Product: Attruby and Beyonttra; Quality below floor (4.0 < 4.0).

Is BBIO overvalued or undervalued?

BridgeBio Pharma, Inc. trades at a P/E of N/A (forward -315.3). TrendMatrix value score: 5.4/10. Verdict: Sell.

What do analysts say about BBIO?

29 analysts cover BBIO with a consensus score of 4.1/5. Average price target: $108.

What does BridgeBio Pharma, Inc. do?BridgeBio Pharma commercializes Attruby (acoramidis) for ATTR-CM in the U.S. and develops therapies for genetic...

BridgeBio Pharma commercializes Attruby (acoramidis) for ATTR-CM in the U.S. and develops therapies for genetic diseases. Attruby generated $362.4 million in U.S. net product revenues in 2025; Beyonttra contributed $105.0 million in license revenue via Bayer (Europe) and Alexion (Japan). Three Phase 3 programs—infigratinib, BBP-418, and encaleret—each reported positive data in 2025-2026 with NDA submissions planned for 2026.

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