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Alnylam Pharmaceuticals, Inc. (ALNY) Stock Analysis

HoldModerate Confidence

Healthcare · Biotechnology

Alnylam Pharmaceuticals, Inc. discovers, develops, manufactures, and commercializes therapeutics based on ribonucleic acid interference in the United States, Europe, and internationally. The company offers ONPATTRO for hereditary transthyretin-mediated (hATTR) amyloidosis;... Read more

$328.70+16.2% upside
Score 6.4/10Target $381.92Reward/Risk 1.4:1

TrendMatrix rates Alnylam Pharmaceuticals, Inc. (ALNY) as Hold with moderate confidence. The stock trades at $328.70 with +16.2% upside to the $381.92 price target. Overall score: 6.4/10 across 10 analysis dimensions. Reward/risk ratio: 1.4:1.

Passes 3/5 gates (positive momentum, clean insider activity, no SEC red flags). Fails on favorable risk/reward ratio. Suitability: moderate.

Val5.3Qual6.8Grw10.0Mom6.3Sent9.0Ins3.2Peer4.5Tech3.0Risk6.26.4OVERALL

Investment Thesis

+ Sector modifier (): +1.2
+ Strong earnings beat streak (3/4)
+ Strong growth profile
- Leverage penalty (D/E 3.8): -1.5
- Below 200-day MA

Fundamentals

P/E (TTM)132.2
P/E (Fwd)21.4
Mkt Cap$40.9B
EV/EBITDA73.1
Profit Mgn8.4%
ROE73.3%
Rev Growth84.9%
Beta0.38
DividendNone
Analysts36
Frequently Asked Questions
Is ALNY stock a buy right now?

TrendMatrix rates Alnylam Pharmaceuticals, Inc. (ALNY) as Hold with moderate confidence. Score 6.4/10.

What is the ALNY stock price target?

Take-profit target: $381.92 (+16.2% upside). Reward/risk ratio: 1.4:1. Stop-loss: $290.63.

What are the risks of investing in ALNY?

Leverage penalty (D/E 3.8): -1.5; Below 200-day MA.

Is ALNY overvalued or undervalued?

Alnylam Pharmaceuticals, Inc. trades at a P/E of 132.2 (forward 21.4). TrendMatrix value score: 5.3/10. Verdict: Hold.

What do analysts say about ALNY?

36 analysts cover ALNY with a consensus score of 4.0/5. Average price target: $449.

What does Alnylam Pharmaceuticals, Inc. do?Alnylam Pharmaceuticals, Inc. discovers, develops, manufactures, and commercializes therapeutics based on ribonucleic...

Alnylam Pharmaceuticals, Inc. discovers, develops, manufactures, and commercializes therapeutics based on ribonucleic acid interference in the United States, Europe, and internationally. The company offers ONPATTRO for hereditary transthyretin-mediated (hATTR) amyloidosis; AMVUTTRA for ATTR and hATTR amyloidosis; Leqvio for hypercholesterolemia; Qfitlia for hemophilia A or B; GIVLAARI for acute hepatic porphyria; and OXLUMO for primary hyperoxaluria type 1. It also develops a range of products in Phase 3 trial, such as Nucresiran for ATTR amyloidosis; Zilebesiran for hypertension; Cemdisiran for myasthenia gravis, paroxysmal nocturnal hemoglobinuria, and geographic atrophy; and Elebsiran for hepatitis D virus infections. In addition, the company is developing various products in Phase 2 trial, including Rapirosiran for metabolic dysfunction-associated steatohepatitis; ALN-ANG3 for diabetic kidney disease; ALN-4324 for type 2 diabetes mellitus; Mivelsiran for cerebral amyloid angiopathy, as well as in Phase 1 trial for Alzheimer's disease; and ALN-6400 for bleeding disorders. Further, it develops a range of products in Phase 1 trial, such as ALN-2232 for obesity and weight management; ALN-PNP for non-alcoholic fatty liver disease; ALN-APOC3 for dyslipidemia; ALN-CIDEB for metabolic dysfunction-associated steatohepatitis; ALN-HTT02 for Huntington's disease; ALN-5288 for Alzheimer's disease; ALN-SOD for SOD1 amyotrophic lateral sclerosis; ALN-SNCA for Parkinson's disease; AG-236 for polycythemia vera; ALN-CFB for paroxysmal nocturnal hemoglobinuria; ALN-BCAT for hepatocellular carcinoma; and ALN-4285, ALN-4915, and ALN-F1202 for healthy volunteers. The company has collaborations with Regeneron Pharmaceuticals, Inc.; Roche Holding AG; Sanofi S.A.; Novartis AG; PeptiDream, Inc; Dicerna Pharmaceuticals, Inc.; and Ionis Pharmaceuticals, Inc. Alnylam Pharmaceuticals, Inc. was founded in 2002 and is headquartered in Cambridge, Massachusetts.

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57 NEUTRAL
20d<50d<200dDEATH CROSSSupp $299.62Res $334.80

Price Targets

$291
$382
Upside+16.2%
Reward/Risk1.4:1

Position Sizing

ConvictionNONE
Suggested %0.5%
Max %1%
RegimeRISK_OFF

Risk Alerts

! ASYMMETRY:1.8<2.0
RECOVERYSuitability: Moderate
Momentum 6.3>=5.0
Insider activity: OK
No SEC red flags
Death cross (50MA < 200MA)
Risk/Reward 1.8<2.0