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AUTLAutolus Therapeutics plcSell5.7·$1.63
SellModerate Confidence
Investment thesis

Autolus is growing revenue 118% YoY from a small base but burns cash at -171% of revenue, trades in a downtrend near $1.54, and has no usable analyst target after the raw figure was rejected as implausible.

Thesis pillars

  • Cash Burn Funding Risk→Stable
  • Rapid Revenue Growth→Stable
  • Downtrend Pullback↑Improving
  • +2 more pillars — see the Why tab for full reasoning

Pillars as of Oct 24, 2026, based on the 10-K filed Mar 27, 2026

Full reasoning →

Open full analysis

Autolus Therapeutics plc (AUTL) Stock Analysis

Range Bound setup · Inst Constrain edge

SellGrowthModerate Confidence

Healthcare · Biotechnology

Sell if holding. Engine safety override at $1.63: Quality below floor (2.2 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.7/10. Specifically: Below-average business quality; Below long-term trend.

Autolus Therapeutics markets AUCATZYL (obe-cel), a CD19-targeted CAR T cell therapy for adult relapsed or refractory B-cell precursor acute lymphoblastic leukemia, approved by the FDA in November 2024 and launched in the U.S. in January 2025, with the UK's MHRA and the European... Read more

$1.63+16.6% A.UpsideScore 5.7/10#68 of 241 Biotechnology
QualityF-score3 / 9FCF yield-46.37%
Stop $1.52Resistance target $1.90A.R:R 0.0:1
Analyst consensus$8.75+436.8%8 analysts
$1.90Resistance target
$1.63price
$8.75mean
$11

Sell if holding. Engine safety override at $1.63: Quality below floor (2.2 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.7/10. Specifically: Below-average business quality; Below long-term trend. Chart setup: RSI 41 mid-range, Bollinger mid-band. Score 5.7/10, moderate confidence.

Passes 6/9 gates (positive momentum, clean insider activity, no SEC red flags, news events none recent, semi cycle peak clear, materials cycle peak clear). Suitability: speculative.

news + 30-day 8-K events · 5-min refresh

Recent developments

updated 2026-10-29
TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Tue, Nov 10, 202611d to earnings· next earnings call

Thesis

Rewards
No bull case signals
Risks
DATA_ISSUE: analyst_target_implausible (raw $8.75 vs price $1.63 — ratio 5.4×). Rejected, falling back to technical TP.
Quality below floor (2.2 < 4.0)

Key Metrics

P/E (TTM)—
P/E (Fwd)-2.6
Mkt Cap$434M
EV/EBITDA-2.5
Profit Mgn-238.7%
ROE-133.0%
Rev Growth118.4%
Beta2.14
DividendNone
Rating analysts16

Quality Signals

Piotroski F3/9

Options Flow

P/C0.05bullish
IV228%elevated

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results. How we score · Editorial policy

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About TrendMatrix. TrendMatrix is a publisher of general securities research and market commentary. We publish on a regular schedule. All content is the same for every subscriber in a tier — we do not provide personalized investment advice and we do not take into account any individual subscriber's financial situation, investment objectives, risk tolerance, tax situation, or holdings.

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Performance. Past performance is not indicative of future results. Performance figures reflect the published model only and do not reflect any individual subscriber's actual results.

Methodology · Editorial policy & full disclaimer

Rating Breakdown

2 floor-breakers·1 ceiling hit

Clinical-stage biotech: losses expected pre-commercialisation. Quality floor doesn't distinguish R&D investment from operational decay — components above tell the real story.static

Roe
0.0
Roa
0.0
Operating Margin
0.0
Fcf Quality
0.0
Piotroski F
3.3
Moat
4.2
Current Ratio
8.1
Cash-burning: FCF -171% of revenueNo competitive moatWeak Piotroski F-Score: 3/9Quality concerns

No near-term catalyst priced in. Thesis progression will come from fundamentals grinding, not event reaction.static

Earnings History
0.0
Surprise Avg
0.0
Erm
5.0
Earnings Timing
5.0
News Activity
5.0
Earnings concerns: 0B/3MEarnings in 11 days
GatesMomentum 4.9<5.5 (soft — BUY_NOW allowed but watch)A.R:R UPSIDE_EXHAUSTED (upside=0.0%)EARNINGS PROXIMITY 11d<=14d (soft)Momentum 4.9>=4.5Insider activity: OKNo SEC red flagsNEWS EVENTS NONE RECENTSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARRange BoundSuitability: Speculative
RSI
41 · Neutral
↓ 20D MA↓ 50D MA↓ 200D MAGOLDEN CROSSSupport $1.50Resistance $1.94

Price Targets

$2
$2
A.R:R0.0:1

Position Sizing

ConvictionNone
Suggested %0%
Max %0%
RegimeSteady

Risk Alerts

! DATA_ISSUE: analyst_target_implausible (raw $8.75 vs price $1.63 — ratio 5.4×). Rejected, falling back to technical TP.
! Quality below floor (2.2 < 4.0)

Earnings

M
M
M
M
0/4 beats
Next Earnings2026-11-10 (11d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is AUTL stock a buy right now?

Sell if holding. Engine safety override at $1.63: Quality below floor (2.2 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.7/10. Specifically: Below-average business quality; Below long-term trend. Chart setup: RSI 41 mid-range, Bollinger mid-band. Prior stop was $1.52. Score 5.7/10, moderate confidence.

What is the AUTL stock price target?

Resistance target: $1.90 (+16.6% upside). Prior stop was $1.52. Stop-loss: $1.52.

What are the risks of investing in AUTL?

DATA_ISSUE: analyst_target_implausible (raw $8.75 vs price $1.63 — ratio 5.4×). Rejected, falling back to technical TP.; Quality below floor (2.2 < 4.0).

Is AUTL overvalued or undervalued?

Autolus Therapeutics plc trades at a P/E of N/A (forward -2.6). TrendMatrix value score: 7.8/10. Verdict: Sell.

What do analysts say about AUTL?

16 analysts cover AUTL with a consensus score of 4.3/5. Average price target: $9.

What does Autolus Therapeutics plc do?Autolus Therapeutics markets AUCATZYL (obe-cel), a CD19-targeted CAR T cell therapy for adult relapsed or refractory...

Autolus Therapeutics markets AUCATZYL (obe-cel), a CD19-targeted CAR T cell therapy for adult relapsed or refractory B-cell precursor acute lymphoblastic leukemia, approved by the FDA in November 2024 and launched in the U.S. in January 2025, with the UK's MHRA and the European Commission granting conditional and full marketing authorizations since. The company posted a $287.5 million net loss in 2025 against a $1,386.8 million accumulated deficit, and expects AUCATZYL to generate substantially all of its product revenue for the foreseeable future.

Related stocks: CRMD (CorMedix Inc.) · HRMY (Harmony Biosciences Holdings, I) · ZVRA (Zevra Therapeutics, Inc.) · AUPH (Aurinia Pharmaceuticals Inc) · PHAT (Phathom Pharmaceuticals, Inc.)
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