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ASNDAscendis Pharma A/SSell6.4·$218.06+1.14%
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Ascendis Pharma A/S (ASND) Stock Analysis

SellVALUE-TRAP 1/5Moderate Confidence

Healthcare · Biotechnology

Sell if holding. Multiple concerning factors at $218.06: Leverage penalty (D/E 1.8): -1.0; Consecutive earnings misses (2).

Ascendis Pharma A/S, operates as a biopharmaceutical company that focuses on developing TransCon-based therapies for unmet medical needs in Europe, the United States, and internationally. The company offers SKYTROFA for treating pediatric patients with growth hormone deficiency;... Read more

$218.06+22.5% A.UpsideScore 6.4/10#14 of 157 Biotechnology
QualityF-score4 / 9FCF yield0.84%
Stop $202.80Target $267.04(analyst − 10%)A.R:R 2.6:1
Analyst target$296.71+36.1%17 analysts
$267.04our TP
$218.06price
$296.71mean
$353

Sell if holding. Multiple concerning factors at $218.06: Leverage penalty (D/E 1.8): -1.0; Consecutive earnings misses (2). Chart setup: No clear chart pattern; technical signals are mixed. Score 6.4/10, moderate confidence.

Passes 7/8 gates (positive momentum, favorable risk/reward ratio, clean insider activity, no SEC red flags, earnings proximity no date, semi cycle peak clear, materials cycle peak clear). Suitability: moderate.

TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Thu, Apr 30, 2026· next earnings call

Thesis

Rewards
Strong growth profile
Wide economic moat
Analyst upside: 22%
Risks
Leverage penalty (D/E 1.8): -1.0
Consecutive earnings misses (2)

Key Metrics

P/E (TTM)24.7
P/E (Fwd)19.8
Mkt Cap$14.1B
EV/EBITDA-1341.5
Profit Mgn57.3%
ROE332.7%
Rev Growth144.3%
Beta
DividendNone
Rating analysts26

Quality Signals

Piotroski F4/9MoatWideCompounder

Options Flow

P/C0.27bullish
IV52%elevated

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.

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Performance. Past performance is not indicative of future results. Performance figures reflect the published model only and do not reflect any individual subscriber's actual results.

Methodology · Editorial policy & full disclaimer

Rating Breakdown

1 ceiling hit

GatesMomentum 4.7<5.5 (soft — BUY_NOW allowed but watch)Momentum 4.7>=4.5A.R:R 2.6 ≥ 1.5Insider activity: OKNo SEC red flagsEARNINGS PROXIMITY NO DATESEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARSuitability: Moderate
RSI
29 · Oversold
20D MA 50D MA 200D MAGOLDEN CROSSSupport $203.80Resistance $249.96

Price Targets

$203
$267
A.Upside+22.5%
A.R:R2.6:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Analyst Consensus

Analysts26
Consensus4.4/5
Avg Target$297

Earnings

B
M
M
M
1/4 beats
Next Earnings2026-04-30 (nulld)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is ASND stock a buy right now?

Sell if holding. Multiple concerning factors at $218.06: Leverage penalty (D/E 1.8): -1.0; Consecutive earnings misses (2). Chart setup: No clear chart pattern; technical signals are mixed. Prior stop was $202.80. Score 6.4/10, moderate confidence.

What is the ASND stock price target?

Take-profit target: $267.04 (+22.5% upside). Prior stop was $202.80. Stop-loss: $202.80.

What are the risks of investing in ASND?

Leverage penalty (D/E 1.8): -1.0; Consecutive earnings misses (2).

Is ASND overvalued or undervalued?

Ascendis Pharma A/S trades at a P/E of 24.7 (forward 19.8). TrendMatrix value score: 5.4/10. Verdict: Sell.

What do analysts say about ASND?

26 analysts cover ASND with a consensus score of 4.4/5. Average price target: $297.

What does Ascendis Pharma A/S do?Ascendis Pharma A/S, operates as a biopharmaceutical company that focuses on developing TransCon-based therapies for...

Ascendis Pharma A/S, operates as a biopharmaceutical company that focuses on developing TransCon-based therapies for unmet medical needs in Europe, the United States, and internationally. The company offers SKYTROFA for treating pediatric patients with growth hormone deficiency; and YORVIPATH, a once-daily subcutaneous injection for the treatment of adults with chronic hypoparathyroidism. It is also developing a pipeline of three independent endocrinology rare disease product candidates in clinical development, as well as focuses on advancing oncology therapeutic candidates. The company was incorporated in 2006 and is based in Hellerup, Denmark.

Related stocks: AUPH (Aurinia Pharmaceuticals Inc) · INCY (Incyte Corporation) · ARGX (argenx SE) · ADMA (ADMA Biologics Inc) · HRMY (Harmony Biosciences Holdings, I)
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