Summit Therapeutics Inc. (SMMT) Stock Analysis
Healthcare · Biotechnology
Sell if holding. Engine safety override at $14.19: a dimension score below its floor triggers a hard block regardless of the otherwise-positive setup — overall score 5.0/10 and A.R:R 5.1:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 27%; Elevated put/call ratio: 1.57; Below-average business quality.
Summit Therapeutics is a clinical-stage biopharmaceutical company developing ivonescimab, a PD-1/VEGF bispecific antibody licensed from Akeso, for NSCLC and colorectal cancer globally. The company submitted a BLA in Q4 2025 with an FDA PDUFA date of November 14, 2026; it... Read more
Sell if holding. Engine safety override at $14.19: a dimension score below its floor triggers a hard block regardless of the otherwise-positive setup — overall score 5.0/10 and A.R:R 5.1:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 27%; Elevated put/call ratio: 1.57; Below-average business quality. Chart setup: No clear chart pattern; technical signals are mixed. Score 5.0/10, moderate confidence.
Passes 7/8 gates (favorable risk/reward ratio, clean insider activity, no SEC red flags, news events none recent, earnings proximity 59d clear, semi cycle peak clear, materials cycle peak clear). Fails on weak momentum. Suitability: moderate.
Recent developments
updated 2026-06-13Recent Developments — Summit Therapeutics Inc.
Latest news
- NEWS Summit Therapeutics Withdraws Previously Announced Proposed $500M Underwritten Public Offering Of Shares Due To Market C — benzinga Jun 11, 2026 negative
- NEWS Oil Jumps On Iran Strikes, Nasdaq 100 Falls On Hot Inflation: Stock Market Today — benzinga Jun 10, 2026 neutral
- NEWS Super Micro Computer, Summit Therapeutics And Other Big Stocks Moving Lower In Wednesday's Pre-Market Session — benzinga Jun 10, 2026 negative
- NEWS 12 Health Care Stocks Moving In Tuesday's After-Market Session — benzinga Jun 9, 2026 neutral
- NEWS Summit Therapeutics Launches $500M Public Stock Offering To Fund Ivonescimab Development — benzinga Jun 9, 2026 positive
Generated 2026-06-15T18:11:47Z.
Upcoming dated catalysts
Thesis
Key Metrics
Quality Signals
Options Flow
Concentration Risks(10-K Item 1A)
- HIGHpipelineivonescimab10-K Item 1A: 'We depend heavily on the success of ivonescimab. If we are unable to successfully develop and commercialize ivonescimab'
- HIGHSupplierAkeso10-K Item 1A: 'We rely on the use of third parties, including Akeso, to manufacture our product candidate.'
Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.
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Rating Breakdown
4 floor-breakers·1 ceiling hit
Quality below the gate floor. Component breakdown shows what dragged the score down.static
Volatile — 8.2% daily ATR makes tight stops impractical. Position-size conservatively.static
No near-term catalyst priced in. Thesis progression will come from fundamentals grinding, not event reaction.static
Ranks in the bottom of its industry peers on the composite signal. Better names in the same sector exist.static
Price Targets
Position Sizing
Risk Alerts
Earnings
Verdict History
Frequently Asked Questions
Sell if holding. Engine safety override at $14.19: a dimension score below its floor triggers a hard block regardless of the otherwise-positive setup — overall score 5.0/10 and A.R:R 5.1:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 27%; Elevated put/call ratio: 1.57; Below-average business quality. Chart setup: No clear chart pattern; technical signals are mixed. Prior stop was $13.03. Score 5.0/10, moderate confidence.
Take-profit target: $24.78 (+76.9% upside). Prior stop was $13.03. Stop-loss: $13.03.
Concentration risk — Pipeline: ivonescimab; Concentration risk — Supplier: Akeso; Quality below floor (1.8 < 4.0).
Summit Therapeutics Inc. trades at a P/E of N/A (forward -11.1). TrendMatrix value score: 9.0/10. Verdict: Sell.
24 analysts cover SMMT with a consensus score of 3.8/5. Average price target: $28.
What does Summit Therapeutics Inc. do?Summit Therapeutics is a clinical-stage biopharmaceutical company developing ivonescimab, a PD-1/VEGF bispecific...
Summit Therapeutics is a clinical-stage biopharmaceutical company developing ivonescimab, a PD-1/VEGF bispecific antibody licensed from Akeso, for NSCLC and colorectal cancer globally. The company submitted a BLA in Q4 2025 with an FDA PDUFA date of November 14, 2026; it generates no product revenue and funds operations through equity issuances.