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GLUEMonte Rosa Therapeutics, Inc.Sell4.2·$18.30+7.02%
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Monte Rosa Therapeutics, Inc. (GLUE) Stock Analysis

Range Bound setup

SellModerate Confidence

Healthcare · Biotechnology

Sell if holding. Engine safety override at $18.30: Quality below floor (1.4 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.2/10 and A.R:R 4.4:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 19%; Elevated put/call ratio: 2.00; Below-average business quality.

Monte Rosa Therapeutics, Inc., a clinical-stage biotechnology company, engages in the development of novel small molecule precision medicines that employ the body's natural mechanisms to selectively degrade therapeutically relevant proteins. The company develops orally... Read more

$18.30+54.3% A.UpsideScore 4.2/10#145 of 157 Biotechnology
QualityF-score2 / 9FCF yield-5.01%
Stop $16.96Target $28.13(analyst − 13%)A.R:R 4.4:1
Analyst target$32.33+76.7%6 analysts
$28.13our TP
$18.30price
$32.33mean
$37

Sell if holding. Engine safety override at $18.30: Quality below floor (1.4 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.2/10 and A.R:R 4.4:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 19%; Elevated put/call ratio: 2.00; Below-average business quality. Chart setup: RSI 46 mid-range, Bollinger mid-band. Score 4.2/10, moderate confidence.

Passes 8/8 gates (positive momentum, favorable risk/reward ratio, clean insider activity, no SEC red flags, news events none recent, earnings proximity 54d clear, semi cycle peak clear, materials cycle peak clear). Suitability: aggressive.

news + 30-day 8-K events · 5-min refresh

Recent developments

updated 2026-06-13

Recent Developments — Monte Rosa Therapeutics, Inc.

Generated 2026-06-15T18:11:46Z.

TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Thu, Aug 6, 202654d to earnings· next earnings call

Thesis

Rewards
No bull case signals
Risks
Quality below floor (1.4 < 4.0)

Key Metrics

P/E (TTM)
P/E (Fwd)-10.0
Mkt Cap$1.5B
EV/EBITDA-6.5
Profit Mgn0.0%
ROE-32.6%
Rev Growth-95.0%
Beta1.60
DividendNone
Rating analysts15

Quality Signals

Piotroski F2/9

Options Flow

P/C2.00bearish
IV146%elevated
Max Pain$25+36.6% vs spot

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.

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Performance. Past performance is not indicative of future results. Performance figures reflect the published model only and do not reflect any individual subscriber's actual results.

Methodology · Editorial policy & full disclaimer

Rating Breakdown

4 floor-breakers

Quality below the gate floor. Component breakdown shows what dragged the score down.static

Roe
0.0
Roa
0.0
Net Margin
0.0
Fcf Quality
0.0
Piotroski F
2.2
Moat
2.5
Current Ratio
5.0
Cash-burning: FCF -180% of revenueNo competitive moatWeak Piotroski F-Score: 2/9Quality concerns

Volatile — 6.2% daily ATR makes tight stops impractical. Position-size conservatively.static

Days To Cover
0.0
Volatility
0.0
Put Call
0.0
Implied Vol
0.0
Debt Equity
0.0
Short Interest
1.6
Beta
4.7
Max Pain Risk
7.0
High short interest justified: 19%Elevated put/call: 2.00High IV: 146%

Ranks in the bottom of its industry peers on the composite signal. Better names in the same sector exist.static

Growth Rank
0.2
Value Rank
1.4
Quality Rank
4.7

No near-term catalyst priced in. Thesis progression will come from fundamentals grinding, not event reaction.static

Surprise Avg
0.5
Earnings History
3.3
Erm
5.0
Earnings Timing
5.0
Earnings concerns: 2B/2M
GatesMomentum 5.7>=5.5A.R:R 4.4 ≥ 1.5Insider activity: OKNo SEC red flagsNEWS EVENTS NONE RECENTEARNINGS PROXIMITY 54d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARRange BoundSuitability: Aggressive
RSI
46 · Neutral
20D MA 50D MA 200D MAGOLDEN CROSSSupport $16.11Resistance $20.36

Price Targets

$17
$28
A.Upside+53.7%
A.R:R4.4:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Quality below floor (1.4 < 4.0)

Earnings

B
B
M
M
2/4 beats
Next Earnings2026-08-06 (54d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is GLUE stock a buy right now?

Sell if holding. Engine safety override at $18.30: Quality below floor (1.4 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.2/10 and A.R:R 4.4:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 19%; Elevated put/call ratio: 2.00; Below-average business quality. Chart setup: RSI 46 mid-range, Bollinger mid-band. Prior stop was $16.96. Score 4.2/10, moderate confidence.

What is the GLUE stock price target?

Take-profit target: $28.13 (+54.3% upside). Prior stop was $16.96. Stop-loss: $16.96.

What are the risks of investing in GLUE?

Quality below floor (1.4 < 4.0).

Is GLUE overvalued or undervalued?

Monte Rosa Therapeutics, Inc. trades at a P/E of N/A (forward -10.0). TrendMatrix value score: 5.4/10. Verdict: Sell.

What do analysts say about GLUE?

15 analysts cover GLUE with a consensus score of 4.3/5. Average price target: $32.

What does Monte Rosa Therapeutics, Inc. do?Monte Rosa Therapeutics, Inc., a clinical-stage biotechnology company, engages in the development of novel small...

Monte Rosa Therapeutics, Inc., a clinical-stage biotechnology company, engages in the development of novel small molecule precision medicines that employ the body's natural mechanisms to selectively degrade therapeutically relevant proteins. The company develops orally bioavailable molecular glue degraders (MGDs), such as MRT-2359 for the treatment of MYC-driven tumors; MRT-6160 for the treatment of neurologic and systemic autoimmune and inflammatory diseases; and MRT-8102 for the treatment of inflammatory diseases driven by IL-1a, IL-1ß and IL-18, as well as damage-associated molecular patterns. In addition, it develops CDK2 to treat multiple cancers, including ovarian, endometrial, gastric and breast. Further, its pipeline includes programs in immunology and inflammation indications, oncology, cardiovascular, metabolic, and genetic diseases. The company also develops QuEEN, a discovery engine, to enable its target-centric MGD discovery and development approach and its rational design of MGD product candidates. It has a strategic collaboration and licensing agreement with F. Hoffmann-La Roche Ltd.; and Novartis. The company was incorporated in 2019 and is headquartered in Boston, Massachusetts.

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