Skip to main content

Guardant Health, Inc. (GH) Stock Analysis

SellModerate Confidence

Healthcare · Diagnostics & Research

Sell if holding. Engine safety override at $114.00: Quality below floor (3.7 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.7/10. Specifically: High short interest: 10%; Elevated put/call ratio: 1.91; Below-average business quality.

Guardant Health is a precision oncology company that develops and commercializes liquid biopsy tests (Guardant360, Shield, Guardant Infinity) for cancer detection, therapy selection, and monitoring. It earns revenue primarily from clinical test volumes reimbursed by Medicare and... Read more

$114.00+2.2% A.UpsideScore 5.7/10#8 of 26 Diagnostics & Research
QualityF-score5 / 9FCF yield-0.66%
Stop $106.92Target $117.47(analyst − 10%)A.R:R 0.1:1
Analyst target$130.52+14.5%21 analysts
$117.47our TP
$114.00price
$130.52mean
$90
$190

Sell if holding. Engine safety override at $114.00: Quality below floor (3.7 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.7/10. Specifically: High short interest: 10%; Elevated put/call ratio: 1.91; Below-average business quality. Chart setup: No recognized chart pattern (not a breakout, bounce, continuation, recovery, falling knife, or range) — technicals mixed. Score 5.7/10, moderate confidence.

Passes 7/8 gates (positive momentum, clean insider activity, no SEC red flags, news events none recent, earnings proximity 70d clear, semi cycle peak clear, materials cycle peak clear). Fails on favorable risk/reward ratio. Suitability: aggressive.

Recent Developments — Guardant Health, Inc.

Generated 2026-05-20T23:21:20Z.

Thesis

Rewards
No bull case signals
Risks
Target reached (2.2% upside)
Quality below floor (3.7 < 4.0)

Key Metrics

P/E (TTM)
P/E (Fwd)-159.1
Mkt Cap$13.0B
EV/EBITDA-33.4
Profit Mgn-40.1%
ROE
Rev Growth48.3%
Beta1.49
DividendNone
Rating analysts33

Quality Signals

Piotroski F5/9MoatNarrow

Options Flow

P/C1.91bearish
IV62%elevated
Max Pain$50-56.1% vs spot

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results. Full disclaimer

Rating Breakdown

4 floor-breakers·1 ceiling hit

Technicals below the gate floor. Component breakdown shows what dragged the score down.static

Bollinger
0.0
Support Resistance
0.0
Gap
5.0
52w Position
9.0

Ranks in the bottom of its industry peers on the composite signal. Better names in the same sector exist.static

Quality Rank
0.0
Value Rank
0.4
Growth Rank
8.8
Industry growth leader

Unprofitable operations — net margin -40.1%. Quality floor flags this regardless of sector context.static

Roa
0.0
Operating Margin
0.0
Net Margin
0.0
Fcf Quality
0.0
Piotroski F
5.6
Moat
7.0
Current Ratio
8.3
Gross Margin
9.0
Cash-burning: FCF -8% of revenue

Priced at a premium — multiples above sector norms. Needs delivery on growth + margins to justify.static

Ps
2.0
Analyst Target
5.0
Low model confidence on this dimension (33%).
GatesA.R:R 0.1 < 1.5@spotMomentum 8.5>=5.5Insider activity: OKNo SEC red flagsNEWS EVENTS NONE RECENTEARNINGS PROXIMITY 70d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARSuitability: Aggressive
RSI
84 · Overbought
20D MA 50D MA 200D MAGOLDEN CROSSSupport $79.01Resistance $115.08

Price Targets

$107
$117
A.Upside+3.0%
A.R:R0.1:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Target reached (2.2% upside)
! Quality below floor (3.7 < 4.0)
! Reward/Risk 0.1:1 at current price — below 1.5:1 minimum

Earnings

B
B
B
M
3/4 beats
Next Earnings2026-07-29 (70d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is GH stock a buy right now?

Sell if holding. Engine safety override at $114.00: Quality below floor (3.7 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.7/10. Specifically: High short interest: 10%; Elevated put/call ratio: 1.91; Below-average business quality. Chart setup: No recognized chart pattern (not a breakout, bounce, continuation, recovery, falling knife, or range) — technicals mixed. Prior stop was $106.92. Score 5.7/10, moderate confidence.

What is the GH stock price target?

Take-profit target: $117.47 (+2.2% upside). Prior stop was $106.92. Stop-loss: $106.92.

What are the risks of investing in GH?

Target reached (2.2% upside); Quality below floor (3.7 < 4.0).

Is GH overvalued or undervalued?

Guardant Health, Inc. trades at a P/E of N/A (forward -159.1). TrendMatrix value score: 3.8/10. Verdict: Sell.

What do analysts say about GH?

33 analysts cover GH with a consensus score of 4.3/5. Average price target: $131.

What does Guardant Health, Inc. do?Guardant Health is a precision oncology company that develops and commercializes liquid biopsy tests (Guardant360,...

Guardant Health is a precision oncology company that develops and commercializes liquid biopsy tests (Guardant360, Shield, Guardant Infinity) for cancer detection, therapy selection, and monitoring. It earns revenue primarily from clinical test volumes reimbursed by Medicare and commercial insurers, and from biopharmaceutical research partnerships.

Related stocks: VCYT (Veracyte, Inc.) · MEDP (Medpace Holdings, Inc.) · WAT (Waters Corporation) · SHC (Sotera Health Company) · ADPT (Adaptive Biotechnologies Corpor)