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BillionToOne, Inc. (BLLN) Stock Analysis

Range Bound setup

HoldModerate Confidence

Healthcare · Diagnostics & Research

Hold if already holding. Not a fresh buy at $83.38, but acceptable to hold if already in. Reasons: Concentration risk — Product: molecular diagnostic tests; Concentration risk — Counterparty: third-party payors (90.0%).

BillionToOne provides single-molecule next-generation sequencing (smNGS) diagnostic tests for prenatal genetic screening (UNITY suite) and oncology liquid biopsy (Northstar Select, Northstar Response). Revenue comes primarily from third-party payor reimbursement for its... Read more

$83.38+22.8% A.UpsideScore 5.6/10#11 of 26 Diagnostics & Research
QualityF-score9 / 9FCF yield0.44%
Stop $77.54Target $102.41(analyst − 13%)A.R:R 1.5:1
Analyst target$117.71+41.2%7 analysts
$102.41our TP
$83.38price
$117.71mean
$145

Hold if already holding. Not a fresh buy at $83.38, but acceptable to hold if already in. Reasons: Concentration risk — Product: molecular diagnostic tests; Concentration risk — Counterparty: third-party payors (90.0%). Chart setup: RSI 56 mid-range, Bollinger mid-band. Maintain position. Not compelling to add more. Score 5.6/10, moderate confidence.

Passes 7/8 gates (favorable risk/reward ratio, clean insider activity, no SEC red flags, news events none recent, earnings proximity 77d clear, semi cycle peak clear, materials cycle peak clear). Fails on weak momentum. Suitability: aggressive.

Recent Developments — BillionToOne, Inc.

Generated 2026-05-21T00:51:20Z.

Thesis

Rewards
Sector modifier (Healthcare): +0.5
Strong growth profile
Wide economic moat
Risks
Concentration risk — Product: molecular diagnostic tests
Concentration risk — Counterparty: third-party payors (90.0%)
Expensive valuation

Key Metrics

P/E (TTM)152.4
P/E (Fwd)79.9
Mkt Cap$3.8B
EV/EBITDA78.8
Profit Mgn7.0%
ROE8.7%
Rev Growth83.8%
Beta
DividendNone
Rating analysts14

Quality Signals

Piotroski F9/9MoatWide

Options Flow

P/C6.60bearish
IV82%elevated
Max Pain$40-52.0% vs spot

Concentration Risks(10-K Item 1A)

  • HIGHProductmolecular diagnostic tests
    10-K Item 1A: 'We primarily generate revenue from sales of our molecular diagnostic tests and we are highly dependent on them for our success'
  • HIGHcounterpartythird-party payors90%
    10-K Item 1A: 'Reimbursement from third-party payors for our tests represented more than 90% of our revenue for each of the years ended December 31, 2025 and 2024'

Material Events(8-K, last 90d)

  • 2026-03-04Item 5.02LOW
    Board approved the BillionToOne Annual Incentive Plan effective January 1, 2026, to attract, retain, and motivate top performing employees. Compensatory arrangement only; no officer departures or appointments reported.
    SEC filing →

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results. Full disclaimer

Rating Breakdown

3 floor-breakers·1 ceiling hit

Momentum below the gate floor. Component breakdown shows what dragged the score down.static

Macd
0.0
Obv
1.0
Volume
3.1
Rsi
4.5
Ma Position
4.5
Volume distribution (falling OBV)

Ranks in the bottom of its industry peers on the composite signal. Better names in the same sector exist.static

Value Rank
0.6
Quality Rank
4.5
Growth Rank
9.2
Industry growth leader

Priced at a premium — multiples above sector norms. Needs delivery on growth + margins to justify.static

Pe
0.0
Forward Pe
1.0
Ps
3.0
Analyst Target
7.5
Peg Ratio
7.7
Forward P/E: 79.9xPEG: 0.88
GatesMomentum 2.6<4.5A.R:R 1.5 ≥ 1.5Insider activity: OKNo SEC red flagsNEWS EVENTS NONE RECENTEARNINGS PROXIMITY 77d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARRange BoundSuitability: Aggressive
RSI
56 · Neutral
20D MA 50D MA 200D MASupport $70.81Resistance $107.00

Price Targets

$78
$102
A.Upside+22.8%
A.R:R1.5:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeRisk-Off

Risk Alerts

! Momentum score 2.6/10 — below 4.5 minimum

Earnings

B
M
M
M
1/4 beats
Next Earnings2026-08-05 (77d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is BLLN stock a buy right now?

Hold if already holding. Not a fresh buy at $83.38, but acceptable to hold if already in. Reasons: Concentration risk — Product: molecular diagnostic tests; Concentration risk — Counterparty: third-party payors (90.0%). Chart setup: RSI 56 mid-range, Bollinger mid-band. Maintain position. Not compelling to add more. Target $102.41 (+22.8%), stop $77.54 (−7.5%), A.R:R 1.5:1. Score 5.6/10, moderate confidence.

What is the BLLN stock price target?

Take-profit target: $102.41 (+22.8% upside). Target $102.41 (+22.8%), stop $77.54 (−7.5%), A.R:R 1.5:1. Stop-loss: $77.54.

What are the risks of investing in BLLN?

Concentration risk — Product: molecular diagnostic tests; Concentration risk — Counterparty: third-party payors (90.0%); Expensive valuation.

Is BLLN overvalued or undervalued?

BillionToOne, Inc. trades at a P/E of 152.4 (forward 79.9). TrendMatrix value score: 3.8/10. Verdict: Hold.

What do analysts say about BLLN?

14 analysts cover BLLN with a consensus score of 4.2/5. Average price target: $118.

What does BillionToOne, Inc. do?BillionToOne provides single-molecule next-generation sequencing (smNGS) diagnostic tests for prenatal genetic...

BillionToOne provides single-molecule next-generation sequencing (smNGS) diagnostic tests for prenatal genetic screening (UNITY suite) and oncology liquid biopsy (Northstar Select, Northstar Response). Revenue comes primarily from third-party payor reimbursement for its molecular diagnostic tests, with >90% from third-party payors in both 2024 and 2025. The patented QCT platform enables single-DNA-molecule sensitivity, differentiating it from conventional NGS.

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