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Amgen Inc. (AMGN) Stock Analysis

Temp Headwind edge

SellVALUE-TRAP 1/5High Confidence

Healthcare · Drug Manufacturers - General

Sell if holding. Analyst target reached at $328.81 — A.R:R is negative (-0.1) — price has exceeded the analyst target. Reward from here is too thin for a buy — the engine flags exit. Additional concerns: Concentration risk — Geographic: Puerto Rico.

Amgen is one of the largest independent biotechnology companies, discovering, developing, manufacturing, and commercializing human therapeutics in a single operating segment with presence in approximately 100 countries. Revenue comes from product sales including Repatha, ENBREL,... Read more

$328.81+7.8% A.UpsideScore 5.5/10#7 of 16 Drug Manufacturers - General
Stop $315.68Target $352.25(resistance)A.R:R -0.1:1
Analyst target$352.73+7.3%30 analysts
$352.25our TP
$328.81price
$352.73mean
$200
$432

Sell if holding. Analyst target reached at $328.81 — A.R:R is negative (-0.1) — price has exceeded the analyst target. Reward from here is too thin for a buy — the engine flags exit. Additional concerns: Concentration risk — Geographic: Puerto Rico. Chart setup: No recognized chart pattern (not a breakout, bounce, continuation, recovery, falling knife, or range) — technicals mixed. Score 5.5/10, high confidence.

Passes 5/7 gates (clean insider activity, no SEC red flags, news boost earnings 0.80, earnings proximity no date, semi cycle peak clear). Fails on weak momentum and favorable risk/reward ratio. Suitability: moderate.

Thesis

Rewards
Strong earnings beat streak (3/4)
High-quality business
Recent Earnings detected in news
Risks
Concentration risk — Geographic: Puerto Rico
Analyst target reached - limited upside remaining
Leverage penalty (D/E 6.2): -1.5

Key Metrics

P/E (TTM)24.1
P/E (Fwd)14.8
Mkt Cap$186.9B
EV/EBITDA12.9
Profit Mgn21.0%
ROE101.3%
Rev Growth5.8%
Beta
Dividend2.91%
Rating analysts43

Quality Signals

Piotroski F7/9

Options Flow

P/C0.64bullish
IV47%normal
Max Pain$240-27.0% vs spot

Concentration Risks(10-K Item 1A)

  • HIGHGeographicPuerto Rico
    10-K Item 1A: 'We perform a substantial majority of our commercial manufacturing activities at our facility in the U.S. territory of Puerto Rico'

Material Events(8-K, last 90d)

  • 2026-04-22Item 5.02LOW
    EVP David M. Reese retiring as CTO effective June 30, 2026. Responsibilities redistributed to EVPs Bradner, Gordon, and Griffith effective June 1, 2026. No successor named as CTO.
    SEC filing →
  • 2026-01-30Item 1.02MEDIUM
    Amgen and Kyowa Kirin Co., Ltd. agreed to terminate their License and Collaboration Agreement dated June 1, 2021. Termination effective upon receipt of regulatory approval. No reason cited beyond mutual agreement.
    SEC filing →

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results. Full disclaimer

Rating Breakdown

2 floor-breakers

Momentum below the gate floor. Component breakdown shows what dragged the score down.static

Macd
0.0
Volume
0.0
Obv
1.0
Ma Position
4.0
Rsi
8.3
Uptrend pullback (RSI 32) - buy opportunityVolume distribution (falling OBV)Above 200-day MA

Growth below the gate floor. Component breakdown shows what dragged the score down.static

Earnings Growth
2.9
Revenue Growth
3.9
GatesMomentum 2.7<4.5A.R:R -0.1=NEGATIVEInsider activity: OKNo SEC red flagsNEWS BOOST EARNINGS 0.80EARNINGS PROXIMITY NO DATESEMI CYCLE PEAK CLEARSuitability: Moderate
RSI
32 · Neutral
20D MA 50D MA 200D MAGOLDEN CROSSSupport $325.44Resistance $359.44

Price Targets

$316
$352
A.Upside+7.1%
A.R:R-0.1:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeCautious

Risk Alerts

! Target reached (-0.7% upside)
! Momentum score 2.7/10 — below 4.5 minimum
! Negative risk/reward — downside exceeds upside

Earnings

B
B
B
M
3/4 beats
Next Earnings2026-04-30 (nulld)

Verdict History

reverse chrono — latest first
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Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is AMGN stock a buy right now?

Sell if holding. Analyst target reached at $328.81 — A.R:R is negative (-0.1) — price has exceeded the analyst target. Reward from here is too thin for a buy — the engine flags exit. Additional concerns: Concentration risk — Geographic: Puerto Rico. Chart setup: No recognized chart pattern (not a breakout, bounce, continuation, recovery, falling knife, or range) — technicals mixed. Prior stop was $315.68. Score 5.5/10, high confidence.

What is the AMGN stock price target?

Take-profit target: $352.25 (+7.8% upside). Prior stop was $315.68. Stop-loss: $315.68.

What are the risks of investing in AMGN?

Concentration risk — Geographic: Puerto Rico; Analyst target reached - limited upside remaining; Leverage penalty (D/E 6.2): -1.5.

Is AMGN overvalued or undervalued?

Amgen Inc. trades at a P/E of 24.1 (forward 14.8). TrendMatrix value score: 5.5/10. Verdict: Sell.

What do analysts say about AMGN?

43 analysts cover AMGN with a consensus score of 3.5/5. Average price target: $353.

What does Amgen Inc. do?Amgen is one of the largest independent biotechnology companies, discovering, developing, manufacturing, and...

Amgen is one of the largest independent biotechnology companies, discovering, developing, manufacturing, and commercializing human therapeutics in a single operating segment with presence in approximately 100 countries. Revenue comes from product sales including Repatha, ENBREL, Otezla, TEPEZZA, and IMDELLTRA. A substantial majority of commercial manufacturing occurs at its Puerto Rico facility.

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