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ELVNEnliven Therapeutics, Inc.Sell5.2·$46.25+14.59%
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Enliven Therapeutics, Inc. (ELVN) Stock Analysis

Breakout setup

SellModerate Confidence

Healthcare · Biotechnology

Sell if holding. Engine safety override at $46.25: a dimension score below its floor triggers a hard block regardless of the otherwise-positive setup — overall score 5.2/10. Specifically: High short interest: 14%; Elevated put/call ratio: 4.50; Below-average business quality.

Enliven Therapeutics is a clinical-stage biopharmaceutical company developing ELVN-001, a highly selective BCR-ABL tyrosine kinase inhibitor in Phase 1 ENABLE trial for chronic myeloid leukemia (CML), with Phase 3 ENABLE-2 planned for 2H 2026. The company has no approved... Read more

$46.25+13.4% A.UpsideScore 5.2/10#78 of 157 Biotechnology
QualityF-score4 / 9FCF yield-1.87%
Stop $42.90Target $52.30(analyst − 13%)A.R:R 0.9:1
Analyst target$60.11+30.0%9 analysts
$52.30our TP
$46.25price
$60.11mean
$80

Sell if holding. Engine safety override at $46.25: a dimension score below its floor triggers a hard block regardless of the otherwise-positive setup — overall score 5.2/10. Specifically: High short interest: 14%; Elevated put/call ratio: 4.50; Below-average business quality. Chart setup: Golden cross, above all MAs, RSI 60, MACD bullish. Score 5.2/10, moderate confidence.

Passes 7/8 gates (positive momentum, clean insider activity, no SEC red flags, news events none recent, earnings proximity 61d clear, semi cycle peak clear, materials cycle peak clear). Fails on favorable risk/reward ratio. Suitability: aggressive.

news + 30-day 8-K events · 5-min refresh

Recent developments

updated 2026-06-12
TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Wed, Aug 12, 202661d to earnings· next earnings call

Thesis

Rewards
No bull case signals
Risks
Concentration risk — Pipeline: ELVN-001
Concentration risk — Supplier: Pharmaron
Quality below floor (1.6 < 4.0)

Key Metrics

P/E (TTM)
P/E (Fwd)-16.6
Mkt Cap$2.5B
EV/EBITDA-17.4
Profit Mgn0.0%
ROE-26.6%
Rev Growth
Beta0.40
DividendNone
Rating analysts17

Quality Signals

Piotroski F4/9

Options Flow

P/C4.50bearish
IV97%elevated
Max Pain$3-94.6% vs spot

Concentration Risks(10-K Item 1A)

  • HIGHpipelineELVN-001
    10-K Item 1A: 'We are substantially dependent on ELVN-001. If we are unable to advance ELVN-001 through clinical development, obtain regulatory approval and ultimately commercialize or license ELVN-001...our business will be materially harmed.'
  • HIGHSupplierPharmaron
    10-K Item 1: 'we have obtained the custom-manufactured starting materials for active pharmaceutical ingredients ("APIs") manufacture from Pharmaron and Hande Sciences and our good manufacturing practice ("GMP") APIs from Pharmaron.'

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.

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Methodology · Editorial policy & full disclaimer

Rating Breakdown

1 floor-breaker·1 ceiling hit

Quality below the gate floor. Component breakdown shows what dragged the score down.static

Roe
0.0
Roa
0.0
Gross Margin
0.0
Operating Margin
0.0
Net Margin
0.0
Fcf Quality
0.0
Piotroski F
4.4
Moat
4.8
Current Ratio
5.0
Cash-burning (FCF negative)No competitive moatQuality concerns
GatesA.R:R 0.9 < 1.5@spotMomentum 9.1>=5.5Insider activity: OKNo SEC red flagsNEWS EVENTS NONE RECENTEARNINGS PROXIMITY 61d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARBreakoutSuitability: Aggressive
RSI
60 · Neutral
20D MA 50D MA 200D MAGOLDEN CROSSSupport $33.45Resistance $47.36

Price Targets

$43
$52
A.Upside+13.1%
A.R:R0.9:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Quality below floor (1.6 < 4.0)
! asymmetry at 0.9 (below the engine's 1.5 threshold)@spot

Earnings

B
B
M
M
2/4 beats
Next Earnings2026-08-12 (61d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is ELVN stock a buy right now?

Sell if holding. Engine safety override at $46.25: a dimension score below its floor triggers a hard block regardless of the otherwise-positive setup — overall score 5.2/10. Specifically: High short interest: 14%; Elevated put/call ratio: 4.50; Below-average business quality. Chart setup: Golden cross, above all MAs, RSI 60, MACD bullish. Prior stop was $42.90. Score 5.2/10, moderate confidence.

What is the ELVN stock price target?

Take-profit target: $52.30 (+13.4% upside). Prior stop was $42.90. Stop-loss: $42.90.

What are the risks of investing in ELVN?

Concentration risk — Pipeline: ELVN-001; Concentration risk — Supplier: Pharmaron; Quality below floor (1.6 < 4.0).

Is ELVN overvalued or undervalued?

Enliven Therapeutics, Inc. trades at a P/E of N/A (forward -16.6). TrendMatrix value score: 6.0/10. Verdict: Sell.

What do analysts say about ELVN?

17 analysts cover ELVN with a consensus score of 4.3/5. Average price target: $60.

What does Enliven Therapeutics, Inc. do?Enliven Therapeutics is a clinical-stage biopharmaceutical company developing ELVN-001, a highly selective BCR-ABL...

Enliven Therapeutics is a clinical-stage biopharmaceutical company developing ELVN-001, a highly selective BCR-ABL tyrosine kinase inhibitor in Phase 1 ENABLE trial for chronic myeloid leukemia (CML), with Phase 3 ENABLE-2 planned for 2H 2026. The company has no approved products or revenue and is substantially dependent on ELVN-001 for all future commercial value.

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