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SRRKScholar Rock Holding CorporatioSell4.5·$45.37+3.58%
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Scholar Rock Holding Corporatio (SRRK) Stock Analysis

SellModerate Confidence

Healthcare · Biotechnology

Sell if holding. Engine safety override at $45.37: a dimension score below its floor triggers a hard block regardless of the otherwise-positive setup — overall score 4.5/10 and A.R:R 1.9:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 16%; Below-average business quality; Negative price momentum.

Scholar Rock is a pre-commercial biopharma developing apitegromab, an anti-myostatin antibody, as potential first muscle-targeted therapy for SMA; Phase 3 SAPPHIRE was positive but BLA received a CRL in September 2025 due to third-party fill-finish facility GMP issues. Pipeline... Read more

$45.37+17.1% A.UpsideScore 4.5/10#133 of 157 Biotechnology
QualityF-score4 / 9FCF yield-3.28%
Stop $42.39Target $53.38(analyst − 10%)A.R:R 1.9:1
Analyst target$59.31+30.7%16 analysts
$53.38our TP
$45.37price
$59.31mean
$70

Sell if holding. Engine safety override at $45.37: a dimension score below its floor triggers a hard block regardless of the otherwise-positive setup — overall score 4.5/10 and A.R:R 1.9:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 16%; Below-average business quality; Negative price momentum. Chart setup: No clear chart pattern; technical signals are mixed. Score 4.5/10, moderate confidence.

Passes 7/8 gates (favorable risk/reward ratio, clean insider activity, no SEC red flags, news events none recent, earnings proximity 58d clear, semi cycle peak clear, materials cycle peak clear). Fails on weak momentum. Suitability: moderate.

news + 30-day 8-K events · 5-min refresh

Recent developments

updated 2026-06-09

Recent Developments — Scholar Rock Holding Corporatio

Generated 2026-06-15T18:11:47Z.

TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Thu, Aug 6, 202658d to earnings· next earnings call

Thesis

Rewards
No bull case signals
Risks
Concentration risk — Pipeline: apitegromab (SMA)
Concentration risk — Supplier: third-party fill-finish facility
Quality below floor (1.5 < 4.0)

Key Metrics

P/E (TTM)
P/E (Fwd)-18.5
Mkt Cap$5.2B
EV/EBITDA-12.2
Profit Mgn0.0%
ROE-138.9%
Rev Growth
Beta0.69
DividendNone
Rating analysts24

Quality Signals

Piotroski F4/9

Options Flow

P/C0.53bullish
IV78%elevated
Max Pain$35-22.9% vs spot

Concentration Risks(10-K Item 1A)

  • HIGHpipelineapitegromab (SMA)
    10-K Item 1: 'Commercialize apitegromab for children and adults living with SMA. We are developing our first product candidate, apitegromab, for the treatment of patients with SMA.'
  • HIGHSupplierthird-party fill-finish facility
    10-K Item 1A: 'In September 2025, we received a CRL from the FDA citing observations identified during an FDA inspection of a third-party fill-finish facility.'

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.

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Performance. Past performance is not indicative of future results. Performance figures reflect the published model only and do not reflect any individual subscriber's actual results.

Methodology · Editorial policy & full disclaimer

Rating Breakdown

4 floor-breakers

Quality below the gate floor. Component breakdown shows what dragged the score down.static

Roe
0.0
Roa
0.0
Gross Margin
0.0
Operating Margin
0.0
Net Margin
0.0
Fcf Quality
0.0
Moat
4.0
Piotroski F
4.4
Current Ratio
5.0
Cash-burning (FCF negative)No competitive moatQuality concerns

Ranks in the bottom of its industry peers on the composite signal. Better names in the same sector exist.static

Quality Rank
0.0
Value Rank
5.0
Growth Rank
5.0

No near-term catalyst priced in. Thesis progression will come from fundamentals grinding, not event reaction.static

Earnings History
0.0
Surprise Avg
0.0
Erm
5.0
Earnings Timing
5.0
Earnings concerns: 0B/3M

Momentum below the gate floor. Component breakdown shows what dragged the score down.static

Macd
0.0
Volume
2.0
Ma Position
4.0
Obv
4.1
Rsi
5.5
Above 200-day MA
GatesMomentum 3.1<4.5A.R:R 1.9 ≥ 1.5Insider activity: OKNo SEC red flagsNEWS EVENTS NONE RECENTEARNINGS PROXIMITY 58d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARSuitability: Moderate
RSI
44 · Neutral
20D MA 50D MA 200D MAGOLDEN CROSSSupport $43.29Resistance $52.19

Price Targets

$42
$53
A.Upside+17.7%
A.R:R1.9:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Quality below floor (1.5 < 4.0)
! momentum at 3.1 (below the engine's 4.5 threshold)

Earnings

M
M
M
M
0/4 beats
Next Earnings2026-08-06 (58d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is SRRK stock a buy right now?

Sell if holding. Engine safety override at $45.37: a dimension score below its floor triggers a hard block regardless of the otherwise-positive setup — overall score 4.5/10 and A.R:R 1.9:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 16%; Below-average business quality; Negative price momentum. Chart setup: No clear chart pattern; technical signals are mixed. Prior stop was $42.39. Score 4.5/10, moderate confidence.

What is the SRRK stock price target?

Take-profit target: $53.38 (+17.1% upside). Prior stop was $42.39. Stop-loss: $42.39.

What are the risks of investing in SRRK?

Concentration risk — Pipeline: apitegromab (SMA); Concentration risk — Supplier: third-party fill-finish facility; Quality below floor (1.5 < 4.0).

Is SRRK overvalued or undervalued?

Scholar Rock Holding Corporatio trades at a P/E of N/A (forward -18.5). TrendMatrix value score: 7.5/10. Verdict: Sell.

What do analysts say about SRRK?

24 analysts cover SRRK with a consensus score of 4.3/5. Average price target: $59.

What does Scholar Rock Holding Corporatio do?Scholar Rock is a pre-commercial biopharma developing apitegromab, an anti-myostatin antibody, as potential first...

Scholar Rock is a pre-commercial biopharma developing apitegromab, an anti-myostatin antibody, as potential first muscle-targeted therapy for SMA; Phase 3 SAPPHIRE was positive but BLA received a CRL in September 2025 due to third-party fill-finish facility GMP issues. Pipeline also includes SRK-439 (Phase 1) and STK-002-class programs.

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