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PBLSParabilis Medicines, Inc.Sell5.8·$28.17
SellModerate Confidence
Investment thesis

Parabilis Medicines cannot currently be evaluated on price-based measures due to a missing price feed, and the available fundamentals point to margin compression, insider selling, and below-average quality that argue for caution once trading data is restored.

Thesis pillars

  • Value Trap Signals Margin And Insider Selling↓Deteriorating
  • Data Outage Blocks Trade Setup↓Deteriorating
  • Quality Concerns Flagged→Stable
  • +2 more pillars — see the Why tab for full reasoning

Pillars as of Jul 5, 2026

Full reasoning →

Open full analysis

Parabilis Medicines, Inc. (PBLS) Stock Analysis

Range Bound setup

SellQualityModerate Confidence

Healthcare · Biotechnology

Sell if holding. Engine safety override at $28.17: Quality below floor (3.0 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.8/10 and A.R:R 1.9:1 is above the 1.5:1 BUY gate. Specifically: Elevated put/call ratio: 2.62; Below-average business quality.

Parabilis Medicines, Inc. operates as a clinical-stage biopharmaceutical company focused on developing helical peptide therapeutics for disease treatment. The company develops stabilized helical peptide therapeutics through its Helicon discovery platform, targeting proteins that... Read more

$28.17+27.9% A.UpsideScore 5.8/10#56 of 241 Biotechnology
QualityF-score4 / 9FCF yield—
Stop $26.20Analyst target $36.02(−13% haircut)A.R:R 1.9:1
Analyst consensus$41.40+47.0%5 analysts
$36.02Analyst target
$28.17price
$41.40mean
$45

Sell if holding. Engine safety override at $28.17: Quality below floor (3.0 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.8/10 and A.R:R 1.9:1 is above the 1.5:1 BUY gate. Specifically: Elevated put/call ratio: 2.62; Below-average business quality. Chart setup: RSI 50 mid-range, Bollinger mid-band. Score 5.8/10, moderate confidence.

Passes 7/8 gates (positive momentum, favorable risk/reward ratio, clean insider activity, no SEC red flags, news boost analyst 0.60, semi cycle peak clear, materials cycle peak clear). Suitability: speculative.

news + 30-day 8-K events · 5-min refresh

Recent developments

updated 2026-10-29
TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Thu, Nov 12, 202613d to earnings· next earnings call

Thesis

Rewards
Recent Analyst detected in news
Risks
Quality below floor (3.0 < 4.0)

Key Metrics

P/E (TTM)—
P/E (Fwd)-12.9
Mkt Cap$3.5B
EV/EBITDA-14.2
Profit Mgn0.0%
ROE—
Rev Growth—
Beta—
DividendNone
Rating analysts11

Quality Signals

Piotroski F4/9MoatNarrow

Options Flow

P/C2.63bearish
IV85%elevated

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results. How we score · Editorial policy

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About TrendMatrix. TrendMatrix is a publisher of general securities research and market commentary. We publish on a regular schedule. All content is the same for every subscriber in a tier — we do not provide personalized investment advice and we do not take into account any individual subscriber's financial situation, investment objectives, risk tolerance, tax situation, or holdings.

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Conflicts and positions. People who build TrendMatrix, or entities they control, may hold positions, long or short, in securities it covers, and may trade them at any time. Positions are not disclosed individually. Verdicts are generated by an automated model applied by the same rules to every covered stock, and are not adjusted for any position held by the people who build TrendMatrix. We do not accept payment from issuers for coverage.

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Performance. Past performance is not indicative of future results. Performance figures reflect the published model only and do not reflect any individual subscriber's actual results.

Methodology · Editorial policy & full disclaimer

Rating Breakdown

2 floor-breakers·1 ceiling hit

Quality below the gate floor. Component breakdown shows what dragged the score down.static

Gross Margin
0.0
Net Margin
0.0
Piotroski F
4.4
Current Ratio
5.0
Moat
5.5
Quality concerns

No near-term catalyst priced in. Thesis progression will come from fundamentals grinding, not event reaction.static

Earnings History
0.0
Surprise Avg
0.0
Erm
5.0
Earnings Timing
5.0
News Activity
8.0
Earnings in 13 days
GatesEARNINGS PROXIMITY 13d<=14d (soft)Momentum 6.9>=5.5A.R:R 1.9 ≥ 1.5Insider activity: OKNo SEC red flagsNEWS BOOST ANALYST 0.60SEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARRange BoundSuitability: Speculative
RSI
50 · Neutral
↑ 20D MA↓ 50D MA↓ 200D MASupport $22.66Resistance $32.63

Price Targets

$26
$36
A.Upside+27.9%
A.R:R1.9:1

Position Sizing

ConvictionNone
Suggested %0%
Max %0%
RegimeSteady

Risk Alerts

! Quality below floor (3.0 < 4.0)

Earnings

M
M
M
M
0/4 beats
Next Earnings2026-11-12 (13d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is PBLS stock a buy right now?

Sell if holding. Engine safety override at $28.17: Quality below floor (3.0 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.8/10 and A.R:R 1.9:1 is above the 1.5:1 BUY gate. Specifically: Elevated put/call ratio: 2.62; Below-average business quality. Chart setup: RSI 50 mid-range, Bollinger mid-band. Prior stop was $26.20. Score 5.8/10, moderate confidence.

What is the PBLS stock price target?

Analyst target: $36.02 (+27.9% upside). Prior stop was $26.20. Stop-loss: $26.20.

What are the risks of investing in PBLS?

Quality below floor (3.0 < 4.0).

Is PBLS overvalued or undervalued?

Parabilis Medicines, Inc. trades at a P/E of N/A (forward -12.9). TrendMatrix value score: 9.0/10. Verdict: Sell.

What do analysts say about PBLS?

11 analysts cover PBLS with a consensus score of 4.4/5. Average price target: $41.

What does Parabilis Medicines, Inc. do?Parabilis Medicines, Inc. operates as a clinical-stage biopharmaceutical company focused on developing helical peptide...

Parabilis Medicines, Inc. operates as a clinical-stage biopharmaceutical company focused on developing helical peptide therapeutics for disease treatment. The company develops stabilized helical peptide therapeutics through its Helicon discovery platform, targeting proteins that are traditionally considered undruggable. Its pipeline includes functional inhibitors of intracellular protein-protein interactions, targeted protein degraders, and targeted radiopharmaceuticals, with a lead clinical program, FOG-001, that acts as a TCF-blocking beta-catenin inhibitor for cancer treatment. The company integrates artificial intelligence and data science into drug discovery, trial design, and clinical strategy optimization. Parabilis Medicines serves clients in the healthcare and life sciences industries, including clinical research organizations and medical professionals involved in oncology and cancer treatment. The company was founded in 2015 and is based in Cambridge, Massachusetts.

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