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AZNAstraZeneca PLCHold5.8·$178.75-1.94%
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AstraZeneca PLC (AZN) Stock Analysis

HoldModerate Confidence

Healthcare · Drug Manufacturers - General

Hold if already holding. Not a fresh buy at $178.75, but acceptable to hold if already in. Reasons: Thin upside margin: 9.3%; Negative momentum.

AstraZeneca PLC, a biopharmaceutical company, focuses on the discovery, development, manufacture, and commercialization of prescription medicines. The company offers Imjudo, Datroway, Iressa, Tagrisso, Imfinzi, Lynparza, Calquence, Enhertu, Orpathys, Truqap, Zoladex, Faslodex,... Read more

$178.75+9.3% A.UpsideScore 5.8/10#5 of 16 Drug Manufacturers - General
QualityF-score8 / 9FCF yield2.32%
IncomeYield1.73%(5y avg 2.11%)Payout47.70%sustainable
Stop $170.69Target $195.31(analyst − 13%)A.R:R 1.9:1
Analyst target$224.49+25.6%10 analysts
$195.31our TP
$178.75price
$224.49mean
$245

Hold if already holding. Not a fresh buy at $178.75, but acceptable to hold if already in. Reasons: Thin upside margin: 9.3%; Negative momentum. Chart setup: No clear chart pattern; technical signals are mixed. Maintain position. Not compelling to add more. Score 5.8/10, moderate confidence.

Passes 6/7 gates (favorable risk/reward ratio, clean insider activity, no SEC red flags, earnings proximity 45d clear, semi cycle peak clear, materials cycle peak clear). Fails on weak momentum. Suitability: moderate.

news + 30-day 8-K events · 5-min refresh

Recent developments

updated 2026-06-13
TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Mon, Jul 27, 202645d to earnings· next earnings call

Thesis

Rewards
Strong earnings beat streak (3/4)
High-quality business
Wide economic moat
Risks
Thin upside margin: 9.3%
Negative momentum

Key Metrics

P/E (TTM)27.5
P/E (Fwd)22.7
Mkt Cap$282.7B
EV/EBITDA15.4
Profit Mgn17.2%
ROE23.5%
Rev Growth12.5%
Beta0.21
Dividend1.73%
Rating analysts35

Quality Signals

Piotroski F8/9MoatWideCompounder

Options Flow

P/C2.45bearish
IV47%normal

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.

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About TrendMatrix. TrendMatrix is a publisher of general securities research and market commentary. We publish on a regular schedule. All content is the same for every subscriber in a tier — we do not provide personalized investment advice and we do not take into account any individual subscriber's financial situation, investment objectives, risk tolerance, tax situation, or holdings.

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Performance. Past performance is not indicative of future results. Performance figures reflect the published model only and do not reflect any individual subscriber's actual results.

Methodology · Editorial policy & full disclaimer

Rating Breakdown

1 floor-breaker

Price action weak — below key moving averages, no momentum carry. Needs a base before trend-continuation setups apply.static

Obv
1.0
Ma Position
2.5
Rsi
3.5
Macd
3.9
Volume
4.8
Volume distribution (falling OBV)
GatesMomentum 3.1<4.5A.R:R 1.9 ≥ 1.5Insider activity: OKNo SEC red flagsEARNINGS PROXIMITY 45d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARSuitability: Moderate
RSI
39 · Neutral
20D MA 50D MA 200D MASupport $174.60Resistance $191.50

Price Targets

$171
$195
A.Upside+9.3%
A.R:R1.9:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! momentum at 3.1 (below the engine's 4.5 threshold)

Earnings

B
B
B
M
3/4 beats
Next Earnings2026-07-27 (45d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is AZN stock a buy right now?

Hold if already holding. Not a fresh buy at $178.75, but acceptable to hold if already in. Reasons: Thin upside margin: 9.3%; Negative momentum. Chart setup: No clear chart pattern; technical signals are mixed. Maintain position. Not compelling to add more. Target $195.31 (+9.3%), stop $170.69 (−4.7%), A.R:R 1.9:1. Score 5.8/10, moderate confidence.

What is the AZN stock price target?

Take-profit target: $195.31 (+9.3% upside). Target $195.31 (+9.3%), stop $170.69 (−4.7%), A.R:R 1.9:1. Stop-loss: $170.69.

What are the risks of investing in AZN?

Thin upside margin: 9.3%; Negative momentum.

Is AZN overvalued or undervalued?

AstraZeneca PLC trades at a P/E of 27.5 (forward 22.7). TrendMatrix value score: 5.4/10. Verdict: Hold.

What do analysts say about AZN?

35 analysts cover AZN with a consensus score of 4.1/5. Average price target: $224.

What does AstraZeneca PLC do?AstraZeneca PLC, a biopharmaceutical company, focuses on the discovery, development, manufacture, and commercialization...

AstraZeneca PLC, a biopharmaceutical company, focuses on the discovery, development, manufacture, and commercialization of prescription medicines. The company offers Imjudo, Datroway, Iressa, Tagrisso, Imfinzi, Lynparza, Calquence, Enhertu, Orpathys, Truqap, Zoladex, Faslodex, Crestor, Andexxa, Onglyza, Symlin, XIGDUO XR, Atacand, Atacand HCT, Atacand Plus, Farxiga/Forxiga, Plendil, Modip, Splendil, Munobal, Flodil, Tenormin, Tenormine, Prenormine, Atenol, Zestril, Brilinta/Brilique, Komboglyze, Qtern, Wainua, Byetta, Lokelma, Seloken ZOK, Toprol-XL, Betaloc ZOK, XIGDUO, Accolate, Accoleit, Vanticon, Bricanyl Respules, Eklira Genuair/Tudorza/Bretaris, Pulmicort Turbuhaler, Symbicort Turbuhaler, Airsupra, Bricanyl Turbuhaler, Fasenra, Rhinocort, Tezspire, Bevespi Aerosphere, Daliresp/Daxas, Oxis Turbuhaler, Saphnelo, Breztri Aerosphere, Duaklir Genuair, Pulmicort Respules, and Symbicort pMDI. It also provides Beyfortus, Kavigale, Evusheld, Fluenz/FluMist, Synagis, Kanuma, Ultomiris, Koselugo, Voydeya, Soliris, Strensiq, Nexium, and other medicines. The company offers its products for ocology, cardiovascular, renal and metabolism, respiratory & immunology, vaccines and immune, and therapies rare diseases. It serves primary and specialty care physicians through distributors and local representative offices in the United Kingdom, the Americas, rest of Europe, Asia, Africa, and Australasia. It has a strategic agreement with Tempus and Pathos to develop the largest multimodal foundation model in oncology; CSPC Pharmaceutical Group Limited to advance the discovery and development of novel oral candidates, with the potential to treat diseases across multiple indications; and Nucs AI Inc. to develop AI-driven Response Prediction for Therapeutic Radioconjugates. The company was formerly known as Zeneca Group PLC and changed its name to AstraZeneca PLC in April 1999. AstraZeneca PLC was incorporated in 1992 and is headquartered in Cambridge, the United Kingdom.

Related stocks: NVO (Novo Nordisk A/S) · LLY (Eli Lilly and Company) · GILD (Gilead Sciences, Inc.) · BMY (Bristol-Myers Squibb Company) · BIIB (Biogen Inc.)
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