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AZNAstraZeneca PLCBuy Wait5.5·$169.51
Buy WaitModerate Confidence
Investment thesis

A wide economic moat, strong margins at 17%, a strong Piotroski F-Score of 8/9, and a 3-of-4 earnings beat record underpin a high-quality franchise that offers 10.2% headroom to the target with a 2.3-to-1 risk/reward — the sole near-term drag is weakening price momentum, which keeps the setup in a holding pattern rather than an active buy.

Thesis pillars

  • Wide Moat Quality Franchise→Stable
  • Earnings Beat Track Record↓Deteriorating
  • Momentum Headwind Weakening Price Action→Stable
  • +2 more pillars — see the Why tab for full reasoning

Pillars as of Jul 3, 2026

Full reasoning →

Open full analysis

AstraZeneca PLC (AZN) Stock Analysis

Buy WaitQualityModerate Confidence

Healthcare · Drug Manufacturers - General

Earnings in 1 day (2026-10-30). Expect elevated volatility around the report — consider waiting for post-earnings price action before new entries.

Wait for pullback to $165.75. At $169.51 the A.R:R is 0.7:1 — below the 1.5:1 minimum for BUY_NOW. Engine's entry $165.75 (Atr Pullback Sticky) is the shallowest technical level that clears the 2:1 A.R:R minimum. Key risks: Thin upside margin: 6.1%; Weak growth.

AstraZeneca PLC, a biopharmaceutical company, focuses on the discovery, development, manufacture, and commercialization of prescription medicines. The company offers Imjudo, Datroway, Iressa, Tagrisso, Imfinzi, Lynparza, Calquence, Enhertu, Orpathys, Truqap, Zoladex, Faslodex,... Read more

$169.51+6.1% A.UpsideScore 5.5/10#8 of 16 Drug Manufacturers - General
QualityF-score8 / 9FCF yield1.95%
IncomeYield1.88%(5y avg 2.05%)Payout46.95%sustainable
Entry $165.75(Atr Pullback Sticky)Stop $158.07Target $179.79(analyst − 13%)A.R:R 0.7:1
Analyst consensus$206.66+21.9%12 analysts
$179.79our TP
$169.51price
$206.66mean
$158
$240

Wait for pullback to $165.75. At $169.51 the A.R:R is 0.7:1 — below the 1.5:1 minimum for BUY_NOW. Engine's entry $165.75 (Atr Pullback Sticky) is the shallowest technical level that clears the 2:1 A.R:R minimum. Key risks: Thin upside margin: 6.1%; Weak growth. Chart setup: No clear chart pattern; technical signals are mixed. Earnings in 1 day. Wait until post-earnings. Score 5.5/10, moderate confidence.

Passes 4/7 gates (clean insider activity, no SEC red flags, semi cycle peak clear, materials cycle peak clear). Fails on weak momentum and favorable risk/reward ratio and earnings proximity 1d<=7d. Suitability: moderate.

news + 30-day 8-K events · 5-min refresh

Recent developments

updated 2026-10-29
TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Fri, Oct 30, 20261d to earnings· next earnings call

Thesis

Rewards
Sector modifier (Healthcare): +0.5
Wide economic moat
Risks
Thin upside margin: 6.1%
Weak growth

Key Metrics

P/E (TTM)25.3
P/E (Fwd)14.9
Mkt Cap$262.9B
EV/EBITDA14.3
Profit Mgn17.0%
ROE22.0%
Rev Growth6.4%
Beta0.21
Dividend1.88%
Rating analysts34

Quality Signals

Piotroski F8/9MoatWideCompounder✓

Options Flow

P/C0.55bullish
IV39%normal
Max Pain$110-35.1% vs spot

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results. How we score · Editorial policy

Show full disclosure ▾

About TrendMatrix. TrendMatrix is a publisher of general securities research and market commentary. We publish on a regular schedule. All content is the same for every subscriber in a tier — we do not provide personalized investment advice and we do not take into account any individual subscriber's financial situation, investment objectives, risk tolerance, tax situation, or holdings.

Not investment advice. TrendMatrix is not a registered investment adviser. Our content is for informational and educational purposes only. Consult your own licensed investment adviser, broker, or tax professional before making any investment decision.

Conflicts and positions. People who build TrendMatrix, or entities they control, may hold positions, long or short, in securities it covers, and may trade them at any time. Positions are not disclosed individually. Verdicts are generated by an automated model applied by the same rules to every covered stock, and are not adjusted for any position held by the people who build TrendMatrix. We do not accept payment from issuers for coverage.

No paid promotion. TrendMatrix does not accept payment from any issuer, broker, or third party in exchange for coverage of any security.

No fiduciary duty. No fiduciary, advisory, or agency relationship is created between you and TrendMatrix by reading our content or subscribing to our service.

Performance. Past performance is not indicative of future results. Performance figures reflect the published model only and do not reflect any individual subscriber's actual results.

Methodology · Editorial policy & full disclaimer

Rating Breakdown

2 floor-breakers

Growth below the gate floor. Component breakdown shows what dragged the score down.static

Earnings Growth
2.5
Revenue Growth
4.1

Technicals below the gate floor. Component breakdown shows what dragged the score down.static

Support Resistance
2.2
Bollinger
2.5
52w Position
6.2
GatesMomentum 4.4<4.5A.R:R 0.7 < 1.5@spotEARNINGS PROXIMITY 1d<=7dInsider activity: OKNo SEC red flagsSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARSuitability: Moderate
RSI
67 · Neutral
↑ 20D MA↑ 50D MA↓ 200D MADEATH CROSSSupport $154.00Resistance $173.91

Price Targets

$158
$166
$180
A.Upside+6.1%
A.R:R0.7:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeRisk-Off

Risk Alerts

! Earnings in 1 day - binary event risk
! momentum at 4.4 (below the engine's 4.5 threshold)
! asymmetry at 0.7 (below the engine's 1.5 threshold)@spot

Earnings

B
B
B
M
3/4 beats
Next Earnings2026-10-30 (1d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is AZN stock a buy right now?

Wait for pullback to $165.75. At $169.51 the A.R:R is 0.7:1 — below the 1.5:1 minimum for BUY_NOW. Engine's entry $165.75 (Atr Pullback Sticky) is the shallowest technical level that clears the 2:1 A.R:R minimum. Key risks: Thin upside margin: 6.1%; Weak growth. Chart setup: No clear chart pattern; technical signals are mixed. Earnings in 1 day. Wait until post-earnings. Target $179.79 (+6.1%), stop $158.07 (−7.2%), A.R:R 0.7:1. Score 5.5/10, moderate confidence.

What is the AZN stock price target?

Take-profit target: $179.79 (+6.1% upside). Target $179.79 (+6.1%), stop $158.07 (−7.2%), A.R:R 0.7:1. Stop-loss: $158.07.

What are the risks of investing in AZN?

Thin upside margin: 6.1%; Weak growth.

Is AZN overvalued or undervalued?

AstraZeneca PLC trades at a P/E of 25.3 (forward 14.9). TrendMatrix value score: 6.1/10. Verdict: Buy (Wait for Entry).

What do analysts say about AZN?

34 analysts cover AZN with a consensus score of 4.2/5. Average price target: $207.

What does AstraZeneca PLC do?AstraZeneca PLC, a biopharmaceutical company, focuses on the discovery, development, manufacture, and commercialization...

AstraZeneca PLC, a biopharmaceutical company, focuses on the discovery, development, manufacture, and commercialization of prescription medicines. The company offers Imjudo, Datroway, Iressa, Tagrisso, Imfinzi, Lynparza, Calquence, Enhertu, Orpathys, Truqap, Zoladex, Faslodex, Crestor, Andexxa, Onglyza, Symlin, XIGDUO XR, Atacand, Atacand HCT, Atacand Plus, Farxiga/Forxiga, Plendil, Modip, Splendil, Munobal, Flodil, Tenormin, Tenormine, Prenormine, Atenol, Zestril, Brilinta/Brilique, Komboglyze, Qtern, Wainua, Byetta, Lokelma, Seloken ZOK, Toprol-XL, Betaloc ZOK, XIGDUO, Accolate, Accoleit, Vanticon, Bricanyl Respules, Eklira Genuair/Tudorza/Bretaris, Pulmicort Turbuhaler, Symbicort Turbuhaler, Airsupra, Bricanyl Turbuhaler, Fasenra, Rhinocort, Tezspire, Bevespi Aerosphere, Daliresp/Daxas, Oxis Turbuhaler, Saphnelo, Breztri Aerosphere, Duaklir Genuair, Pulmicort Respules, and Symbicort pMDI. It also provides Beyfortus, Kavigale, Evusheld, Fluenz/FluMist, Synagis, Kanuma, Ultomiris, Koselugo, Voydeya, Soliris, Strensiq, Nexium, and other medicines. The company offers its products for ocology, cardiovascular, renal and metabolism, respiratory & immunology, vaccines and immune, and therapies for rare diseases. It serves primary and specialty care physicians through distributors and local representative offices in the United Kingdom, USA, rest of Europe, Asia, Africa, and Australasia. It has a strategic agreement with Tempus and Pathos to develop the multimodal foundation model in oncology; CSPC Pharmaceutical Group Limited to advance the discovery and development of oral candidates; Nucs AI Inc. to develop AI-driven Response Prediction for Therapeutic Radioconjugates; and Carterra, Inc. to advances lab-in-the-loop drug discovery through new scientific research collaboration. The company was formerly known as Zeneca Group PLC and changed its name to AstraZeneca PLC in April 1999. AstraZeneca PLC was incorporated in 1992 and is based in Cambridge, the United Kingdom.

Related stocks: LLY (Eli Lilly and Company) · BMY (Bristol-Myers Squibb Company) · AMGN (Amgen Inc.) · ABBV (AbbVie Inc.) · GSK (GSK plc)
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