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AstraZeneca PLC (AZN) Stock Analysis

SellModerate Confidence

Healthcare · Drug Manufacturers - General

Sell if holding. At $184.69, A.R:R 1.1:1 is below the 1.5:1 minimum. Reward from here is too thin for a buy — the engine flags exit. Additional concerns: Negative momentum; Thin upside margin: 5.5%.

AstraZeneca PLC, a biopharmaceutical company, focuses on the discovery, development, manufacture, and commercialization of prescription medicines. The company offers Imjudo, Datroway, Iressa, Tagrisso, Imfinzi, Lynparza, Calquence, Enhertu, Orpathys, Truqap, Zoladex, Faslodex,... Read more

$184.69+5.5% A.UpsideScore 5.4/10#9 of 16 Drug Manufacturers - General
Stop $176.92Target $194.78(analyst − 13%)A.R:R 1.1:1
Analyst target$223.89+21.2%10 analysts
$194.78our TP
$184.69price
$223.89mean
$243

Sell if holding. At $184.69, A.R:R 1.1:1 is below the 1.5:1 minimum. Reward from here is too thin for a buy — the engine flags exit. Additional concerns: Negative momentum; Thin upside margin: 5.5%. Chart setup: No recognized chart pattern (not a breakout, bounce, continuation, recovery, falling knife, or range) — technicals mixed. Score 5.4/10, moderate confidence.

Passes 4/6 gates (clean insider activity, no SEC red flags, earnings proximity 87d clear, semi cycle peak clear). Fails on weak momentum and favorable risk/reward ratio. Suitability: moderate.

Thesis

Rewards
Strong earnings beat streak (3/4)
Risks
Thin upside margin: 5.5%
Negative momentum

Key Metrics

P/E (TTM)28.3
P/E (Fwd)24.1
Mkt Cap$290.5B
EV/EBITDA15.8
Profit Mgn17.2%
ROE23.5%
Rev Growth12.5%
Beta0.28
Dividend1.69%
Rating analysts36

Quality Signals

Piotroski F8/9

Options Flow

P/C0.02bullish
IV44%normal
Max Pain$145-21.5% vs spot

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results. Full disclaimer

Rating Breakdown

1 floor-breaker

Price action weak — below key moving averages, no momentum carry. Needs a base before trend-continuation setups apply.static

Macd
0.0
Volume
0.0
Obv
1.0
Ma Position
2.5
Rsi
3.0
Capitulation risk (RSI 25, below 200MA)Volume distribution (falling OBV)
GatesMomentum 1.3<4.5A.R:R 1.1 < 1.5@spotInsider activity: OKNo SEC red flagsEARNINGS PROXIMITY 87d clearSEMI CYCLE PEAK CLEARSuitability: Moderate
RSI
25 · Oversold
20D MA 50D MA 200D MASupport $181.73Resistance $207.30

Price Targets

$177
$195
A.Upside+5.5%
A.R:R1.1:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Momentum score 1.3/10 — below 4.5 minimum
! Reward/Risk 1.1:1 at current price — below 1.5:1 minimum

Earnings

B
B
B
M
3/4 beats
Next Earnings2026-07-27 (87d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is AZN stock a buy right now?

Sell if holding. At $184.69, A.R:R 1.1:1 is below the 1.5:1 minimum. Reward from here is too thin for a buy — the engine flags exit. Additional concerns: Negative momentum; Thin upside margin: 5.5%. Chart setup: No recognized chart pattern (not a breakout, bounce, continuation, recovery, falling knife, or range) — technicals mixed. Prior stop was $176.92. Score 5.4/10, moderate confidence.

What is the AZN stock price target?

Take-profit target: $194.78 (+5.5% upside). Prior stop was $176.92. Stop-loss: $176.92.

What are the risks of investing in AZN?

Thin upside margin: 5.5%; Negative momentum.

Is AZN overvalued or undervalued?

AstraZeneca PLC trades at a P/E of 28.3 (forward 24.1). TrendMatrix value score: 5.1/10. Verdict: Sell.

What do analysts say about AZN?

36 analysts cover AZN with a consensus score of 4.1/5. Average price target: $224.

What does AstraZeneca PLC do?AstraZeneca PLC, a biopharmaceutical company, focuses on the discovery, development, manufacture, and commercialization...

AstraZeneca PLC, a biopharmaceutical company, focuses on the discovery, development, manufacture, and commercialization of prescription medicines. The company offers Imjudo, Datroway, Iressa, Tagrisso, Imfinzi, Lynparza, Calquence, Enhertu, Orpathys, Truqap, Zoladex, Faslodex, Crestor, Andexxa, Onglyza, Symlin, XIGDUO XR, Atacand, Atacand HCT, Atacand Plus, Farxiga/Forxiga, Plendil, Modip, Splendil, Munobal, Flodil, Tenormin, Tenormine, Prenormine, Atenol, Zestril, Brilinta/Brilique, Komboglyze, Qtern, Wainua, Byetta, Lokelma, Seloken ZOK, Toprol-XL, Betaloc ZOK, XIGDUO, Accolate, Accoleit, Vanticon, Bricanyl Respules, Eklira Genuair/Tudorza/Bretaris, Pulmicort Turbuhaler, Symbicort Turbuhaler, Airsupra, Bricanyl Turbuhaler, Fasenra, Rhinocort, Tezspire, Bevespi Aerosphere, Daliresp/Daxas, Oxis Turbuhaler, Saphnelo, Breztri Aerosphere, Duaklir Genuair, Pulmicort Respules, and Symbicort pMDI. It also provides Beyfortus, Kavigale, Evusheld, Fluenz/FluMist, Synagis, Kanuma, Ultomiris, Koselugo, Voydeya, Soliris, Strensiq, Nexium, and other medicines. The company offers its products for ocology, cardiovascular, renal and metabolism, respiratory & immunology, vaccines and immune, and therapies rare diseases. It serves primary and specialty care physicians through distributors and local representative offices in the United Kingdom, the Americas, rest of Europe, Asia, Africa, and Australasia. It has a strategic agreement with Tempus and Pathos to develop the largest multimodal foundation model in oncology; and a strategic research collaboration with CSPC Pharmaceutical Group Limited to advance the discovery and development of novel oral candidates, with the potential to treat diseases across multiple indications. The company was formerly known as Zeneca Group PLC and changed its name to AstraZeneca PLC in April 1999. AstraZeneca PLC was incorporated in 1992 and is headquartered in Cambridge, the United Kingdom.

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