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NUVBNuvation Bio Inc.Sell4.9·$4.58-7.10%
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Nuvation Bio Inc. (NUVB) Stock Analysis

Range Bound setup

SellVALUE-TRAP 1/5Moderate Confidence

Healthcare · Biotechnology

Sell if holding. Engine safety override at $4.58: Risk below floor (2.5 < 3.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.9/10 and A.R:R 8.9:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 26%; Elevated put/call ratio: 10.00; Below-average business quality.

Nuvation Bio Inc., a clinical-stage biopharmaceutical company, focuses on developing product candidates for cancer treatment. The company's lead product candidate is IBTROZI (taletrectinib), a ROS1 inhibitor for the treatment of patients with ROS1+ non-small cell lung cancer. It... Read more

$4.58+134.3% A.UpsideScore 4.9/10#95 of 157 Biotechnology
QualityF-score6 / 9FCF yield-5.83%
Stop $4.26Target $10.73(analyst − 13%)A.R:R 8.9:1
Analyst target$12.33+169.3%9 analysts
$10.73our TP
$4.58price
$12.33mean
$20

Sell if holding. Engine safety override at $4.58: Risk below floor (2.5 < 3.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.9/10 and A.R:R 8.9:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 26%; Elevated put/call ratio: 10.00; Below-average business quality. Chart setup: RSI 52 mid-range, Bollinger mid-band. Score 4.9/10, moderate confidence.

Passes 7/8 gates (favorable risk/reward ratio, clean insider activity, no SEC red flags, news events none recent, earnings proximity 57d clear, semi cycle peak clear, materials cycle peak clear). Fails on weak momentum. Suitability: aggressive.

news + 30-day 8-K events · 5-min refresh

Recent developments

updated 2026-06-10
TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Thu, Aug 6, 202657d to earnings· next earnings call

Thesis

Rewards
No bull case signals
Risks
Risk below floor (2.5 < 3.0)

Key Metrics

P/E (TTM)
P/E (Fwd)-82.2
Mkt Cap$1.7B
EV/EBITDA-9.4
Profit Mgn-102.1%
ROE-39.5%
Rev Growth2598.7%
Beta1.56
DividendNone
Rating analysts17

Quality Signals

Piotroski F6/9MoatNarrow

Options Flow

P/C10.00bearish
IV115%elevated
Max Pain$18+282.1% vs spot

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.

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Performance. Past performance is not indicative of future results. Performance figures reflect the published model only and do not reflect any individual subscriber's actual results.

Methodology · Editorial policy & full disclaimer

Rating Breakdown

2 floor-breakers

Volatile — 8.3% daily ATR makes tight stops impractical. Position-size conservatively.static

Days To Cover
0.0
Volatility
0.0
Put Call
0.0
Implied Vol
0.0
Short Interest
0.9
Beta
4.8
Debt Equity
6.9
Max Pain Risk
7.0
High short interest justified: 26%Elevated put/call: 10.00High IV: 115%

Price action weak — below key moving averages, no momentum carry. Needs a base before trend-continuation setups apply.static

Obv
1.0
Ma Position
2.2
Macd
4.0
Rsi
4.5
Volume
6.1
Volume distribution (falling OBV)Below 200-MA but MA still rising (+6.8%/30d) — pullback in uptrend, not confirmed weakness
GatesMomentum 3.6<4.5A.R:R 8.9 ≥ 1.5Insider activity: OKNo SEC red flagsNEWS EVENTS NONE RECENTEARNINGS PROXIMITY 57d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARRange BoundSuitability: Aggressive
RSI
52 · Neutral
20D MA 50D MA 200D MADEATH CROSSSupport $4.07Resistance $5.64

Price Targets

$4
$11
A.Upside+134.3%
A.R:R8.9:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Risk below floor (2.5 < 3.0)
! momentum at 3.6 (below the engine's 4.5 threshold)

Earnings

B
M
M
M
1/4 beats
Next Earnings2026-08-06 (57d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is NUVB stock a buy right now?

Sell if holding. Engine safety override at $4.58: Risk below floor (2.5 < 3.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.9/10 and A.R:R 8.9:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 26%; Elevated put/call ratio: 10.00; Below-average business quality. Chart setup: RSI 52 mid-range, Bollinger mid-band. Prior stop was $4.26. Score 4.9/10, moderate confidence.

What is the NUVB stock price target?

Take-profit target: $10.73 (+134.3% upside). Prior stop was $4.26. Stop-loss: $4.26.

What are the risks of investing in NUVB?

Risk below floor (2.5 < 3.0).

Is NUVB overvalued or undervalued?

Nuvation Bio Inc. trades at a P/E of N/A (forward -82.2). TrendMatrix value score: 6.2/10. Verdict: Sell.

What do analysts say about NUVB?

17 analysts cover NUVB with a consensus score of 4.1/5. Average price target: $12.

What does Nuvation Bio Inc. do?Nuvation Bio Inc., a clinical-stage biopharmaceutical company, focuses on developing product candidates for cancer...

Nuvation Bio Inc., a clinical-stage biopharmaceutical company, focuses on developing product candidates for cancer treatment. The company's lead product candidate is IBTROZI (taletrectinib), a ROS1 inhibitor for the treatment of patients with ROS1+ non-small cell lung cancer. It is also developing Safusidenib, an inhibitor of mutant isocitrate dehydrogenase 1 in phase 3 clinical trials for the maintenance treatment of high-risk or high-grade IDH1-mutant astrocytoma with safusidenib against placebo. The company was founded in 2018 and is headquartered in New York, New York.

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